Technology Process of 1H-Cyclopent[b]anthracene-5,10-dione,
2-acetyl-2,4,11-tris(acetyloxy)-1-bromo-2,3-dihydro-, trans-
There total 1 articles about 1H-Cyclopent[b]anthracene-5,10-dione,
2-acetyl-2,4,11-tris(acetyloxy)-1-bromo-2,3-dihydro-, trans- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 13 steps
1: 80 percent / NaH / tetrahydrofuran / 14 h
2: 74 percent / H2, H(1+)
3: 95 percent / 2M NaOH, / methanol / 14 h / Ambient temperature
4: diethyl ether / 3 h / Ambient temperature
5: 49 percent / NaCl / ALCl3 / 0.12 h / 180 °C
6: 90 percent / TosOH / 40 h
7: 95 percent / CF3CO2Ag / CH2Cl2 / 0.12 h
8: 80 percent / m-CPBA / CH2Cl2 / 0.33 h / Ambient temperature
9: 95 percent / NaBH4,CeCl3*7H2O / CH2Cl2; methanol / 0.33 h / 0 - 5 °C
10: 82 percent / m-CPBA / CH2Cl2 / 3 h / 80 °C
11: 91 percent / DCC, DMSO, CFCO2H / pyridine / 15 h / Ambient temperature
12: 84 percent / BrSiMe3 / benzene / 3 h / Ambient temperature
13: 88 percent / DMAP / pyridine; CH2Cl2 / 1 h / Ambient temperature
With
dmap; sodium hydroxide; sodium tetrahydroborate; cerium(III) chloride; trimethylsilyl bromide; hydrogen; silver trifluoroacetate; hydrogen cation; sodium hydride; toluene-4-sulfonic acid; dimethyl sulfoxide; 3-chloro-benzenecarboperoxoic acid; dicyclohexyl-carbodiimide; sodium chloride;
aluminium trichloride;
In
tetrahydrofuran; pyridine; methanol; diethyl ether; dichloromethane; benzene;
DOI:10.1016/S0040-4039(00)89110-8
