4-Methyl-5-(4-pyridyl)-4H-1,2,4-triazole-3-thiol

Base Information

Chemical Name:4-Methyl-5-(4-pyridyl)-4H-1,2,4-triazole-3-thiol
CAS No.:3652-32-2
Molecular Formula:C8H8N4S
Molecular Weight:192.244
Hs Code.:2933990090
European Community (EC) Number:858-129-0
DSSTox Substance ID:DTXSID30190024
Nikkaji Number:J51.327J
ChEMBL ID:CHEMBL4852202
Mol file:3652-32-2.mol

Synonyms:3652-32-2;4-Methyl-5-(4-pyridyl)-4H-1,2,4-triazole-3-thiol;4-Methyl-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol;4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol;4-methyl-3-pyridin-4-yl-1H-1,2,4-triazole-5-thione;Pyridine, 4-(3-mercapto-4-methyl-5-(4H-1,2,4-triazolyl))-;2,4-Dihydro-4-methyl-5-(4-pyridinyl)-3H-1,2,4-triazole-3-thione;BRN 0612127;3-Mercapto-4-methyl-5-(4-pyridyl)-1,2,4-triazole;4H-1,2,4-Triazole-3-thiol, 4-methyl-5-(4-pyridyl)-;4-Methyl-5-pyridin-4-yl-2,4-dihydro-3H-1,2,4-triazole-3-thione;Maybridge1_005232;Oprea1_244805;4-methyl-5-(4-pyridyl)-1,2,4-triazole-3-thiol;4-methyl-5-(pyridin-4-yl)-1,2,4-triazole-3-thiol;SCHEMBL1543914;CHEMBL4852202;HMS556F18;4H-1,2,4-Triazole-3-thiol, 4-methyl-5-(4-pyridinyl)-;DTXSID30190024;MFCD00112607;STK004513;STK231780;AKOS000100098;AKOS000273993;PS-6217;LS-131656;BB 0217198;CS-0040662;FT-0677312;EN300-03529;D72678;A874335;SR-01000585630;SR-01000585630-1;4-methyl-5-pyridin-4-yl-4h-1,2,4-triazole-3-thiol;Z56853822;F3369-0319;4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazole-3-thiol #;4-methyl-5-(pyridin-4-yl)-4h-[1,2,4]triazole-3-thiol;4-methyl-5-pyridin-4-yl-4H-[1,2,4]-triazole-3-thiol;4-Methyl-5-(4-pyridinyl)-2H-1,2,4-triazole-3(4H)-thione;2,4-dihydro-4-methy-5-(4-pyridyl)-3H-1,2,4-triazole-3-thione;2,4-Dihydro-4-methyl-5-(4-pyridyl)-3H-1,2,4-triazole-3-thione;4-Methyl-5-pyridin-4-yl-2,4-dihydro-[1,2,4]triazole-3-thione;3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-methyl-5-(4-pyridinyl)-;4-methyl-5-(pyridin-4-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione

Suppliers and Price of 4-Methyl-5-(4-pyridyl)-4H-1,2,4-triazole-3-thiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol
500mg
$ 200.00

SynQuest Laboratories
4-Methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol
250 mg
$ 64.00

SynQuest Laboratories
4-Methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol
500 mg
$ 96.00

SynQuest Laboratories
4-Methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol
1 g
$ 144.00

Matrix Scientific
4-Methyl-5-pyridin-4-yl-4H-[1,2,4]triazole-3-thiol
500mg
$ 178.00

Crysdot
4-Methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol 95+%
5g
$ 380.00

Chemenu
2,4-Dihydro-4-methyl-5-(4-pyridinyl)-3H-1,2,4-triazole-3-thione 95%+
250mg
$ 149.00

Chemenu
2,4-Dihydro-4-methyl-5-(4-pyridinyl)-3H-1,2,4-triazole-3-thione 95%+
100mg
$ 182.00

Chemenu
2,4-Dihydro-4-methyl-5-(4-pyridinyl)-3H-1,2,4-triazole-3-thione 95%+
5g
$ 764.00

Atlantic Research Chemicals
4-Methyl-5-pyridin-4-yl-4H-1,2,4-triazole-3-thiol 95%
1gm:
$ 166.12

Total 17 raw suppliers

Chemical Property of 4-Methyl-5-(4-pyridyl)-4H-1,2,4-triazole-3-thiol

Chemical Property:

Vapor Pressure:0.00161mmHg at 25°C
Melting Point:287 °C
Refractive Index:1.727
Boiling Point:294.6 °C at 760 mmHg
PKA:8.18±0.20(Predicted)
Flash Point:132 °C
PSA：82.40000
Density:1.4 g/cm³
LogP:1.16580
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:192.04696745
Heavy Atom Count:13
Complexity:245

Purity/Quality:

97% ^*data from raw suppliers

4-Methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=NNC1=S)C2=CC=NC=C2

Technology Process of 4-Methyl-5-(4-pyridyl)-4H-1,2,4-triazole-3-thiol

There total 12 articles about 4-Methyl-5-(4-pyridyl)-4H-1,2,4-triazole-3-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 4406-96-6
4-methyl-1-(pyridine-4-yl-carbonyl)-thiosemicarbazide

: 3652-32-2
4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol

Guidance literature:: With sodium hydrogencarbonate; In water; at 120 ℃; for 22h;
DOI:10.1021/acs.jmedchem.7b00443

Reference yield: 84.0%

: 55-22-1
pyridine-4-carboxylic acid

: 6610-29-3
4-methylthiosemicarbazide

: 3652-32-2
4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol

Guidance literature:: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine; In ethyl acetate; N,N-dimethyl-formamide; at 0 - 20 ℃;

Reference yield: 84.0%

: 3652-32-2
4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol

Guidance literature:: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine; In ethyl acetate; N,N-dimethyl-formamide; at 20 ℃; Cooling with ice; Inert atmosphere;