N-(3-{3-[(Piperidin-1-yl)methyl]phenoxy}propyl)hydrazinecarbothioamide

Base Information

• Chemical Name: N-(3-{3-[(Piperidin-1-yl)methyl]phenoxy}propyl)hydrazinecarbothioamide
• CAS No.: 96924-47-9
• Molecular Formula: C16H26N4OS
• Molecular Weight: 322.475
• DSSTox Substance ID: DTXSID60539644
• Wikidata: Q82415432
• Mol file: 96924-47-9.mol

Synonyms:96924-47-9;SCHEMBL10671497;DTXSID60539644;ULUMORRUZNYLRM-UHFFFAOYSA-N;N-(3-{3-[(Piperidin-1-yl)methyl]phenoxy}propyl)hydrazinecarbothioamide;N-[3-[3-(1-piperidinylmethyl) phenoxy]propyl]-hydrazine carbothioamide;N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl] hydrazine carbothioamide;N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-hydrazine carbothioamide;N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]hydrazine carbothioamide

Chemical Property of N-(3-{3-[(Piperidin-1-yl)methyl]phenoxy}propyl)hydrazinecarbothioamide

Chemical Property:

• XLogP3: 1.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 322.18273264
• Heavy Atom Count: 22
• Complexity: 323

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)CC2=CC(=CC=C2)OCCCNC(=S)NN

Technology Process of N-(3-{3-[(Piperidin-1-yl)methyl]phenoxy}propyl)hydrazinecarbothioamide

There total 3 articles about N-(3-{3-[(Piperidin-1-yl)methyl]phenoxy}propyl)hydrazinecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>amine (73278-98-5) → N-<3-<3-(1-Piperidinylmethyl)phenoxy>propyl>hydrazincarbothioamid (96924-47-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 94 percent / ethanol / 1 h

2: 85 percent / methanol / Ambient temperature

3: NH₂NH₂*H₂O / ethanol / 48 h

With hydrazine hydrate; In methanol; ethanol;

DOI:10.1002/ardp.19853180416

Reference yield:

N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>amine (73278-98-5) + hydrazinecarbodithioic acid methyl ester (5397-03-5) → N-<3-<3-(1-Piperidinylmethyl)phenoxy>propyl>hydrazincarbothioamid (96924-47-9)

Guidance literature:

DOI:10.1002/ardp.19853180416

Reference yield:

N-<3-<3-(1-Piperidinylmethyl)phenoxy>propyl>dithiocarbamidsaeure (96924-45-7) → N-<3-<3-(1-Piperidinylmethyl)phenoxy>propyl>hydrazincarbothioamid (96924-47-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / methanol / Ambient temperature

2: NH₂NH₂*H₂O / ethanol / 48 h

With hydrazine hydrate; In methanol; ethanol;

DOI:10.1002/ardp.19853180416

upstream raw materials:

N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>amine

hydrazinecarbodithioic acid methyl ester

N-<3-<3-(1-Piperidinylmethyl)phenoxy>propyl>dithiocarbamidsaeure

Downstream raw materials:

2-(Phenylmethylen)-N-<3-<3-(1-Piperidinylmethyl)phenoxy>propyl>hydrazincarbothioamid