2-(Furan-2-yl)piperidine

Base Information

Chemical Name:2-(Furan-2-yl)piperidine
CAS No.:97073-24-0
Molecular Formula:C₉H₁₃NO
Molecular Weight:151.208
Hs Code.:2933998090
European Community (EC) Number:860-608-4
DSSTox Substance ID:DTXSID00405814
Metabolomics Workbench ID:48694
ChEMBL ID:CHEMBL4560951
Mol file:97073-24-0.mol

Synonyms:2-(furan-2-yl)piperidine;97073-24-0;2-(2-furyl)piperidine;2-(2-Furanyl)piperidine;2-(2-Piperidinyl)furan;2-(uran-2-yl)piperidine;SCHEMBL7015792;CHEMBL4560951;DTXSID00405814;CHEBI:173410;MIJFUNGHFNXZGN-UHFFFAOYSA-N;BBL020695;MFCD02663560;STK893385;AKOS001476404;SB61783;CS-0259967;EN300-74369;N12707;Z1169540072

Suppliers and Price of 2-(Furan-2-yl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(furan-2-yl)piperidine
100mg
$ 90.00

Crysdot
2-(Furan-2-yl)piperidine 97%
1g
$ 452.00

American Custom Chemicals Corporation
2-(2-FURYL)PIPERIDINE 95.00%
1G
$ 925.31

American Custom Chemicals Corporation
2-(2-FURYL)PIPERIDINE 95.00%
5G
$ 1759.28

American Custom Chemicals Corporation
2-(2-FURYL)PIPERIDINE 95.00%
2.5G
$ 1363.65

AK Scientific
2-(Furan-2-yl)piperidine
2.5g
$ 1116.00

AK Scientific
2-(Furan-2-yl)piperidine
100mg
$ 240.00

Total 8 raw suppliers

Chemical Property of 2-(Furan-2-yl)piperidine

Chemical Property:

PSA：25.17000
LogP:2.42300
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:151.099714038
Heavy Atom Count:11
Complexity:127

Purity/Quality:

97% ^*data from raw suppliers

2-(furan-2-yl)piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCNC(C1)C2=CC=CO2

Technology Process of 2-(Furan-2-yl)piperidine

There total 5 articles about 2-(Furan-2-yl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: (S)-6-(furan-2-yl)-1-[(S)-2-(methoxymethyl)pyrrolidin-1-yl]piperidin-2-one

: 1213190-04-5,97073-24-0
(S)-2-(furan-2-yl)piperidine

: C₉H₁₅NO

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 24h; Reflux; Inert atmosphere;
DOI:10.1002/ejoc.201402202

Reference yield:

: 1643933-36-1
(S)-6-(furan-2-yl)-1-[2-(methoxymethyl)pyrrolidin-1-yl]-3,4-dihydropyridin-2(1H)-one

: 1213190-04-5,97073-24-0
(S)-2-(furan-2-yl)piperidine

: C₉H₁₅NO

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; ammonium formate / methanol; water / 4 h / Reflux; Inert atmosphere

2: lithium hexamethyldisilazane / tetrahydrofuran / 24 h / 0 °C / Reflux; Inert atmosphere

With palladium 10% on activated carbon; ammonium formate; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; water;
DOI:10.1002/ejoc.201402202

Reference yield:

: 108-55-4
glutaric anhydride,

: 1213190-04-5,97073-24-0
(S)-2-(furan-2-yl)piperidine

: C₉H₁₅NO

Guidance literature:: Multi-step reaction with 5 steps

1.1: dichloromethane / 1 h / 20 °C / Inert atmosphere

1.2: 5 h / Heating; Inert atmosphere

2.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / 0.5 h / -78 °C / Inert atmosphere

3.1: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran; water / 2 h / Inert atmosphere; Reflux

4.1: palladium 10% on activated carbon; ammonium formate / methanol; water / 4 h / Reflux; Inert atmosphere

5.1: lithium hexamethyldisilazane / tetrahydrofuran / 24 h / 0 °C / Reflux; Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; ammonium formate; potassium hexamethylsilazane; sodium carbonate; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; dichloromethane; water; toluene; 3.1: |Suzuki-Miyaura Coupling;
DOI:10.1002/ejoc.201402202