Piperazine, 1-(diphenylmethyl)-4-(phenylmethyl)-

Base Information

• Chemical Name: Piperazine, 1-(diphenylmethyl)-4-(phenylmethyl)-
• CAS No.: 97095-89-1
• Molecular Formula: C24H26N2
• Molecular Weight: 342.47700
• Mol file: 97095-89-1.mol

Synonyms:1-Benzhydryl-4-benzyl-piperazin;1-benzhydryl-4-benzylpiperazine;1-benzhydryl-4-benzyl-piperazine;

Chemical Property of Piperazine, 1-(diphenylmethyl)-4-(phenylmethyl)-

Chemical Property:

• Melting Point: 120 °C (ethanol)
• PSA: 6.48000
• LogP: 4.46960

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Piperazine, 1-(diphenylmethyl)-4-(phenylmethyl)-

There total 10 articles about Piperazine, 1-(diphenylmethyl)-4-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

diphenylmethylpiperazine (841-77-0) + benzyl chloride (100-44-7) → 1-diphenylmethyl-4-benzylpiperazine (97095-89-1)

Guidance literature:

In methanol; at 150 ℃; for 0.25h; under 5171.62 Torr; Flow reactor;

DOI:10.1002/cssc.201501367

Reference yield: 86.0%

diphenylmethylpiperazine (841-77-0) + benzyl alcohol (100-51-6,185532-71-2) → 1-diphenylmethyl-4-benzylpiperazine (97095-89-1)

Guidance literature:

With 2-butyl-1,3-diphenyl-1,3,2-diazaphospholidine; 1,1'-azodicarbonyl-dipiperidine; In 1,2-dichloro-ethane; at 40 ℃; under 760.051 Torr;

DOI:10.1021/acs.joc.7b00622

Reference yield: 81.0%

diphenylmethylpiperazine (841-77-0) + 2-(benzyloxy)-1,3-diphenyl-1,3,2-diazaphospholidine → 1-diphenylmethyl-4-benzylpiperazine (97095-89-1)

Guidance literature:

With di-isopropyl azodicarboxylate; In dichloromethane; at 40 ℃; for 36h; Inert atmosphere;

DOI:10.1021/acs.orglett.6b03709

upstream raw materials:

1-phenylmethylpiperazine

diphenylchloromethane

diphenylmethylpiperazine

benzaldehyde