Technology Process of Cyclopentanecarboxaldehyde, 2-phenyl-, (1S,2S)-
There total 9 articles about Cyclopentanecarboxaldehyde, 2-phenyl-, (1S,2S)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Acetic acid (1R,2R)-1,2-diphenyl-2-[(R)-2-phenyl-cyclopent-(E)-ylidenemethoxy]-ethyl ester;
With
formic acid;
In
pentane;
for 2h;
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
tetrahydrofuran;
for 3h;
Heating;
DOI:10.1016/S0957-4166(01)00319-6
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 80 percent / n-BuLi / tetrahydrofuran / 3 h / 25 °C
2: 1.) sec.-BuLi, 2.) HgCl2 / 1.) THF, -10 deg C, -5 deg c, 2 h; 2.) 25 deg C, 2 h
With
n-butyllithium; sec.-butyllithium; mercury dichloride;
In
tetrahydrofuran;
DOI:10.1021/ja00303a026
- Guidance literature:
-
With
acetate buffer; acetate buffer (ph 4.5);
(1R,2R)-1,2-diphenyl-1,2-dimethoxyethane;
Yield given. Multistep reaction;
1.) toluene, -45 deg C, 3 h; 2.) 12 h;
DOI:10.1021/ja00203a032
![Acetic acid (1R,2R)-1,2-diphenyl-2-[(R)-2-phenyl-cyclopent-(E)-ylidenemethoxy]-ethyl ester](/Databaselist/images/loading.webp)
