Benzenamine, 4-[1-(4-methoxyphenyl)-1H-imidazol-4-yl]-

Base Information

• Chemical Name: Benzenamine, 4-[1-(4-methoxyphenyl)-1H-imidazol-4-yl]-
• CAS No.: 97814-30-7
• Molecular Formula: C16H15N3O
• Molecular Weight: 265.315
• Mol file: 97814-30-7.mol

Synonyms:

Chemical Property of Benzenamine, 4-[1-(4-methoxyphenyl)-1H-imidazol-4-yl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenamine, 4-[1-(4-methoxyphenyl)-1H-imidazol-4-yl]-

There total 3 articles about Benzenamine, 4-[1-(4-methoxyphenyl)-1H-imidazol-4-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

1-p-methoxyphenyl-4-p-nitrophenylimidazole (97814-23-8) → 1-(p-methoxyphenyl)-4-(p-aminophenyl)imidazole (97814-30-7)

Guidance literature:

With iron; calcium chloride; In ethanol; for 3h; Heating;

Reference yield:

N-(p-Nitrophenacyl)-p-anisidin (26464-53-9) → 1-(p-methoxyphenyl)-4-(p-aminophenyl)imidazole (97814-30-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 82 percent / conc. hydrochloric acid / methanol / 3 h / Heating

2: 77 percent / 15percent nitric acid / 0.5 h / Heating

3: 60 percent / hydrogen / 10percent palladium on charcoal / ethyl acetate; ethanol / 3040 Torr

With hydrogenchloride; hydrogen; nitric acid; palladium on activated charcoal; In methanol; ethanol; ethyl acetate;

Reference yield:

1-(4-Methoxy-phenyl)-4-(4-nitro-phenyl)-1H-imidazole-2-thiol (97814-14-7) → 1-(p-methoxyphenyl)-4-(p-aminophenyl)imidazole (97814-30-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / 15percent nitric acid / 0.5 h / Heating

2: 60 percent / hydrogen / 10percent palladium on charcoal / ethyl acetate; ethanol / 3040 Torr

With hydrogen; nitric acid; palladium on activated charcoal; In ethanol; ethyl acetate;

upstream raw materials:

1-p-methoxyphenyl-4-p-nitrophenylimidazole

N-(p-Nitrophenacyl)-p-anisidin

1-(4-Methoxy-phenyl)-4-(4-nitro-phenyl)-1H-imidazole-2-thiol

Downstream raw materials:

4-Chloro-N-{4-[1-(4-methoxy-phenyl)-1H-imidazol-4-yl]-phenyl}-benzamide