4-(3-Aminopropyl)phenol hydrochloride

Base Information

• Chemical Name: 4-(3-Aminopropyl)phenol hydrochloride
• CAS No.: 57400-89-2
• Molecular Formula: C9H13NO
• Molecular Weight: 151.208
• Hs Code.: 2922299090
• European Community (EC) Number: 696-633-0
• Mol file: 57400-89-2.mol

Synonyms:40829-38-7;SCHEMBL2364489;HWEDSBUVSQNMGU-UHFFFAOYSA-N;MFCD11506666;4-(3-aminopropyl)phenol;hydrochloride;AKOS006228701;3-(4-hydroxyphenyl)propylamine hydrochloride;4-(3-AMINOPROPYL)PHENOL HYDROCHLORIDE;4-(3-Aminopropyl)phenol hydrochloride;95%

Chemical Property of 4-(3-Aminopropyl)phenol hydrochloride

Chemical Property:

• Vapor Pressure: 0.00135mmHg at 25°C
• Melting Point: 103 °C
• Refractive Index: 1.564
• Boiling Point: 288.4 °C at 760 mmHg
• PKA: 10.03±0.15(Predicted)
• Flash Point: 128.2 °C
• PSA: 46.25000
• Density: 1.073 g/cm³
• LogP: 1.98380
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 187.0763918
• Heavy Atom Count: 12
• Complexity: 97.7

Purity/Quality:

98%Min ^*data from raw suppliers

4-(3-AMINOPROPYL)PHENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CCCN)O.Cl

Technology Process of 4-(3-Aminopropyl)phenol hydrochloride

There total 7 articles about 4-(3-Aminopropyl)phenol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.1%

→ 4-(3-aminopropyl)phenol (57400-89-2)

Guidance literature:

Reference yield: 55.0%

3-(p-hydroxyphenyl)propiononitrile (17362-17-3) → 4-(3-aminopropyl)phenol (57400-89-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Heating;

Reference yield: 55.0%

4‐(but‐3‐yn‐1‐yl)phenol → 4-(3-aminopropyl)phenol (57400-89-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Inert atmosphere; Heating;

DOI:10.1021/ja904876q

upstream raw materials:

3-(p-hydroxyphenyl)propiononitrile

3-(4-methoxyphenyl)propionitrile

ammonium hydroxide

3-(4-hydroxyphenyl)prop-2-ene nitrile

Downstream raw materials:

4-(3-[5-nitropyridin-2-yl-amino]propyl)phenol

N-(t-butoxycarbonyl)-3-(4-hydroxyphenyl)-propylamine

tert-butyl N-[3-(4-hydroxyphenyl)propyl]-β-alaninate

4-[3-(Benzyloxycarbonylamino)propyl]phenol