Technology Process of 2-Cyclopenten-1-ol, 2-[7-(3-methoxyphenyl)-4-heptenyl]-3-methyl-, (E)-
There total 5 articles about 2-Cyclopenten-1-ol, 2-[7-(3-methoxyphenyl)-4-heptenyl]-3-methyl-, (E)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
diethyl ether;
at -20 - 0 ℃;
for 1h;
DOI:10.1002/recl.19851040206
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 81 percent Turnov. / dimethylsulfoxide / 16 h / 85 °C
2: 1.) 1.2 M diisobutylaluminium hydride( in toluene), 2.) 2 N HCl / 1.) toluene, -70 deg C, 0.5 h, 2.) RT
3: 60 percent / 1.3 M phenyllythium in ether / tetrahydrofuran / -70 - -30 °C
4: 1.) acetic acid, 4 N sulphuric acid 2.) KOH / 1.) water, reflux, 2h, 2.) EtOH/water, reflux 4h
5: LiAlH4 / diethyl ether / 1 h / -20 - 0 °C
With
hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; sulfuric acid; diisobutylaluminium hydride; acetic acid; phenyllithium;
In
tetrahydrofuran; diethyl ether; dimethyl sulfoxide;
DOI:10.1002/recl.19851040206
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) 1.2 M diisobutylaluminium hydride( in toluene), 2.) 2 N HCl / 1.) toluene, -70 deg C, 0.5 h, 2.) RT
2: 60 percent / 1.3 M phenyllythium in ether / tetrahydrofuran / -70 - -30 °C
3: 1.) acetic acid, 4 N sulphuric acid 2.) KOH / 1.) water, reflux, 2h, 2.) EtOH/water, reflux 4h
4: LiAlH4 / diethyl ether / 1 h / -20 - 0 °C
With
hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; sulfuric acid; diisobutylaluminium hydride; acetic acid; phenyllithium;
In
tetrahydrofuran; diethyl ether;
DOI:10.1002/recl.19851040206
