2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-

Base Information

Chemical Name:2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-
CAS No.:20971-53-3
Molecular Formula:C17H14ClFN2O2
Molecular Weight:332.762
Hs Code.:
European Community (EC) Number:803-377-7
UNII:2Z6WHH283E
DSSTox Substance ID:DTXSID10175152
Nikkaji Number:J41.259G
Wikidata:Q27255842
ChEMBL ID:CHEMBL435684
Mol file:20971-53-3.mol

Synonyms:20971-53-3;2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-;2-Hydroxyethylflurazepam;Ro-07-2750;7-chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-3H-1,4-benzodiazepin-2-one;N(sup 1)-(2-Hydroxyethyl)flurazepam;N-1-(Hydroxyethyl)flurazepam;2Z6WHH283E;CHEMBL435684;Ro 7-2750;Flurazepam, hydroxyethyl;UNII-2Z6WHH283E;1-(2-Hydroxyethyl)flurazepam;Flurazepam, (N-hydroxyethyl)-;SCHEMBL11679711;2-HYDROXY-ETHYLFLURAZEPAM;DTXSID10175152;BDBM50408009;Ro-072750;LS-34214;2-Hydroxyethylflurazepam 0.1 mg/ml in Methanol;2-Hydroxyethylflurazepam 1.0 mg/ml in Methanol;Q27255842;7-chloro-1-(2-hydroxyethyl)-5-(2-fluorophenyl)-1,3-dihyrdo-2H-1,4-benzodiazepin-2-one;7-Chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one;2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-1-(2-HYDROXYETHYL)-;2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(O-FLUOROPHENYL)-1,3-DIHYDRO-1-(2-HYDROXYETHYL)-;7-CHLORO-1-(2-HYDROXYETHYL)-5-(2'-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE;7-CHLORO-1-(2-HYDROXYETHYL)-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE;7-CHLORO-1-(2-HYDROXYETHYL)-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-3H-1,4-BENZODIAZEPIN-2-ONE;tert-Butyl(dimethyl)silyl (1-[tert-butyl(dimethyl)silyl]-5-([tert-butyl(dimethyl)silyl]oxy)-1H-indol-3-yl)acetate

Suppliers and Price of 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
2-Hydroxyethylflurazepam solution 100μg/mL in methanol, ampule of 1mL, certified reference material
901-1ml
$ 42.10

Sigma-Aldrich
2-Hydroxyethylflurazepam solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
1 mL
$ 86.60

Sigma-Aldrich
2-Hydroxyethylflurazepam solution 1.0mg/mL in methanol, ampule of 1mL, certified reference material
902-1ml
$ 83.90

Chemtos
2-HydroxyethylFlurazepammetabolite1mg/ml
1ml of 1 mg
$ 75.00

Total 4 raw suppliers

Chemical Property of 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-

Chemical Property:

Vapor Pressure:1.07E-13mmHg at 25°C
Boiling Point:567.1°Cat760mmHg
PKA:14.42±0.10(Predicted)
Flash Point:296.8°C
PSA：52.90000
Density:1.36g/cm³
LogP:2.15600
Storage Temp.:2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:332.0727835
Heavy Atom Count:23
Complexity:474

Purity/Quality:

99% ^*data from raw suppliers

2-Hydroxyethylflurazepam solution 100μg/mL in methanol, ampule of 1mL, certified reference material ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F,T
Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F)CCO

Technology Process of 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-

There total 2 articles about 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: