Carbamothioic acid, phenyl-, S-2-propenyl ester

Base Information

• Chemical Name: Carbamothioic acid, phenyl-, S-2-propenyl ester
• CAS No.: 99307-07-0
• Molecular Formula: C10H11NOS
• Molecular Weight: 193.269
• Mol file: 99307-07-0.mol

Synonyms:

Chemical Property of Carbamothioic acid, phenyl-, S-2-propenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamothioic acid, phenyl-, S-2-propenyl ester

There total 5 articles about Carbamothioic acid, phenyl-, S-2-propenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

prop-2-ene-1-thiol (870-23-5) + phenyl isocyanate (103-71-9) → S-(2-propenyl) N-phenylmonothiocarbamate (99307-07-0)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 ℃; for 1.5h; Inert atmosphere;

DOI:10.1021/jacs.5b03428

Reference yield: 91.0%

prop-2-ene-1-thiol (870-23-5) + N-methyl-N'-phenyl-N-nitrosourea (21561-99-9) → S-(2-propenyl) N-phenylmonothiocarbamate (99307-07-0)

Guidance literature:

In acetonitrile; at 60 ℃; for 1h;

DOI:10.1246/bcsj.58.2143

Reference yield: 83.0%

O-(2-propenoyl) N-phenylmonothiocarbamate (5816-31-9) → S-(2-propenyl) N-phenylmonothiocarbamate (99307-07-0)

Guidance literature:

With boron trifluoride diethyl etherate; In chloroform; for 1.5h; Ambient temperature;

upstream raw materials:

prop-2-ene-1-thiol

N-methyl-N'-phenyl-N-nitrosourea

O-(2-propenoyl) N-phenylmonothiocarbamate

chlorothioformic acid allyl ester

Refernces

• 1、 Su,Zhang,Liang. "A convenient, one-pot synthesis of thiocarbamates using bis(trichloromethyl) carbonate". . p. 404 - 410. Retrieved 2007/10/03.
• 2、 Kutschy, Peter,Dzurilla, Milan,Koscik, Dusan,Kristian, Pavol. "AN ADVANTAGEOUS SYNTHESIS OF S-(2-PROPENYL) N-ACYLMONOTHIOCARBAMATES BY -SIGMATROPIC REARRANGEMENT OF O-(2-PROPENYL) N-ACYLMONOTHIOCARBAMATES". . p. 1764 - 1772. Retrieved 2007/10/02.