2(1H)-Quinolinone, 3-hydroxy-4-(4-hydroxyphenyl)-

Base Information

Chemical Name:2(1H)-Quinolinone, 3-hydroxy-4-(4-hydroxyphenyl)-
CAS No.:99557-33-2
Molecular Formula:C₁₅H₁₁NO₃
Molecular Weight:253.257
Hs Code.:

Synonyms:2(1H)-Quinolinone,3-hydroxy-4-(4-hydroxyphenyl);

Suppliers and Price of 2(1H)-Quinolinone, 3-hydroxy-4-(4-hydroxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2(1H)-Quinolinone, 3-hydroxy-4-(4-hydroxyphenyl)-

Chemical Property:

PSA：73.32000
LogP:2.60630

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2(1H)-Quinolinone, 3-hydroxy-4-(4-hydroxyphenyl)-

There total 3 articles about 2(1H)-Quinolinone, 3-hydroxy-4-(4-hydroxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 150256-42-1
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)benzoic acid

: 99557-33-2
3-Hydroxy-4-(4-hydroxy-phenyl)-1H-quinolin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: 2-hydroxyethanethiol; 1,8-diazabicyclo[5.4.0]undec-7-ene / 1-methyl-pyrrolidin-2-one / 0.33 h / 20 °C

1.2: 6 h / 20 °C

2.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

3.1: fungal dioxygenase AsqJ; α-ketoglutaric acid; ascorbic acid; iron(II) sulfate; oxygen / N,N-dimethyl-formamide / 3 h / Enzymatic reaction

With α-ketoglutaric acid; oxygen; fungal dioxygenase AsqJ; iron(II) sulfate; 1,8-diazabicyclo[5.4.0]undec-7-ene; trifluoroacetic acid; 2-hydroxyethanethiol; ascorbic acid; In 1-methyl-pyrrolidin-2-one; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/anie.202017086

Reference yield:

: (S)-3-(4-(tert-butoxy)benzyl)-4-methyl-3,4-dihydro-1H-benzo[1,4]diazepine-2,5-dione

: 99557-33-2
3-Hydroxy-4-(4-hydroxy-phenyl)-1H-quinolin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

2: fungal dioxygenase AsqJ; α-ketoglutaric acid; ascorbic acid; iron(II) sulfate; oxygen / N,N-dimethyl-formamide / 3 h / Enzymatic reaction

With α-ketoglutaric acid; oxygen; fungal dioxygenase AsqJ; iron(II) sulfate; trifluoroacetic acid; ascorbic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/anie.202017086

Reference yield:

: (S)-3-(4-hydroxybenzyl)-4-methyl-3,4-dihydro-1H-benzo[1,4]diazepine-2,5-dione

: 99557-33-2
3-Hydroxy-4-(4-hydroxy-phenyl)-1H-quinolin-2-one

Guidance literature:: With α-ketoglutaric acid; oxygen; fungal dioxygenase AsqJ; iron(II) sulfate; ascorbic acid; In N,N-dimethyl-formamide; for 3h; Enzymatic reaction;
DOI:10.1002/anie.202017086