Dioncophylline A

Base Information

Chemical Name:Dioncophylline A
CAS No.:60142-17-8
Molecular Formula:C24H27NO3
Molecular Weight:377.4761
Hs Code.:
DSSTox Substance ID:DTXSID20975569
Nikkaji Number:J1.153.593C,J410.486B
Wikidata:Q82960212
Metabolomics Workbench ID:52052
ChEMBL ID:CHEMBL410597
Mol file:60142-17-8.mol

Synonyms:dioncophylline A

Suppliers and Price of Dioncophylline A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Dioncophylline A

Chemical Property:

Vapor Pressure:8.59E-10mmHg at 25°C
Boiling Point:478.8°Cat760mmHg
Flash Point:243.4°C
PSA：50.72000
Density:1.128g/cm³
LogP:5.46200
XLogP3:5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:377.19909372
Heavy Atom Count:28
Complexity:528

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2=C(C(N1)C)C(=C(C=C2)C3=C4C=CC=C(C4=C(C=C3C)OC)OC)O
Isomeric SMILES:C[C@@H]1CC2=C([C@H](N1)C)C(=C(C=C2)C3=C4C=CC=C(C4=C(C=C3C)OC)OC)O

Technology Process of Dioncophylline A

There total 14 articles about Dioncophylline A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104292-11-7
1-Bromo-4,5-dimethoxy-naphthalene-2-carbonyl chloride

: 60142-17-8,68780-11-0,129519-17-1,129567-02-8
triphyophylline

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / NEt₃, DMAP / CH₂Cl₂

2: 75 percent / Pd(PPh₃)2Cl₂, NaOAc, DMA / 130 °C

3: LAH / tetrahydrofuran

With dmap; bis-triphenylphosphine-palladium(II) chloride; lithium aluminium tetrahydride; sodium acetate; 2,4-dichlorophenoxyacetic acid dimethylamine; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)94589-1

Reference yield:

: 104292-11-7
1-Bromo-4,5-dimethoxy-naphthalene-2-carbonyl chloride

: 60142-17-8,68780-11-0,129519-17-1,129567-02-8
dioncophylline A

Guidance literature:: Multi-step reaction with 4 steps

1: NEt₃, DMAP / CH₂Cl₂

2: Pd(PPh₃)2Cl₂, NaOAc, DMA / 130 °C

3: LAH / tetrahydrofuran

With dmap; bis-triphenylphosphine-palladium(II) chloride; lithium aluminium tetrahydride; sodium acetate; 2,4-dichlorophenoxyacetic acid dimethylamine; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)94589-1

Reference yield:

: 104292-11-7
1-Bromo-4,5-dimethoxy-naphthalene-2-carbonyl chloride

: 60142-17-8,68780-11-0,129519-17-1,129567-02-8
(+)-dioncophylline A

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / NEt₃, DMAP / CH₂Cl₂

2: 75 percent / Pd(PPh₃)2Cl₂, NaOAc, DMA / 130 °C

3: LAH / tetrahydrofuran

With dmap; bis-triphenylphosphine-palladium(II) chloride; lithium aluminium tetrahydride; sodium acetate; 2,4-dichlorophenoxyacetic acid dimethylamine; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)94589-1