Benzenemethanamine, N-methyl-a-(2-phenylethenyl)-, (Z)-

Base Information

• Chemical Name: Benzenemethanamine, N-methyl-a-(2-phenylethenyl)-, (Z)-
• CAS No.: 99948-35-3
• Molecular Formula: C16H17N
• Molecular Weight: 223.318
• Mol file: 99948-35-3.mol

Synonyms:

Chemical Property of Benzenemethanamine, N-methyl-a-(2-phenylethenyl)-, (Z)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenemethanamine, N-methyl-a-(2-phenylethenyl)-, (Z)-

There total 5 articles about Benzenemethanamine, N-methyl-a-(2-phenylethenyl)-, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(4S,5R)-2-Methyl-3,5-diphenyl-4-trimethylsilanyl-isoxazolidine (99948-26-2,99948-27-3,99948-41-1,99948-42-2) → ((Z)-1,3-Diphenyl-allyl)-methyl-amine (99948-35-3)

Guidance literature:

With sodium hydroxide; hydrogen; Raney Ni (W-2); In methanol; for 12h; Ambient temperature;

DOI:10.1021/jo00354a040

Reference yield: 75.0%

(4S,5S)-2-Methyl-3,5-diphenyl-4-trimethylsilanyl-isoxazolidine (99948-26-2,99948-27-3,99948-41-1,99948-42-2) → ((Z)-1,3-Diphenyl-allyl)-methyl-amine (99948-35-3)

Guidance literature:

With hydrogenchloride; zinc; In tetrahydrofuran; at 50 ℃; for 1h;

DOI:10.1021/jo00354a040

Reference yield:

C-phenyl-N-methylnitrone (3376-23-6,7372-59-0,59862-60-1) → ((Z)-1,3-Diphenyl-allyl)-methyl-amine (99948-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent

2: 84 percent / H₂, 20percent aq. NaOH / Raney Ni (W-2) / methanol / 12 h / Ambient temperature

With sodium hydroxide; hydrogen; Raney Ni (W-2); In methanol;

DOI:10.1021/jo00354a040

upstream raw materials:

(4S,5S)-2-Methyl-3,5-diphenyl-4-trimethylsilanyl-isoxazolidine

(4S,5R)-2-Methyl-3,5-diphenyl-4-trimethylsilanyl-isoxazolidine

1-(trimethylsilyl)-2-phenylethene

C-phenyl-N-methylnitrone

Refernces