7H-Pyrrolo[2,3-d]pyrimidine-2-carbonitrile, 6-[[4-(4-acetyl-1-piperazinyl)phenoxy]methyl]-7-[2-(4,4-difluorocyclohexyl)ethyl]-

Base Information

Chemical Name:7H-Pyrrolo[2,3-d]pyrimidine-2-carbonitrile, 6-[[4-(4-acetyl-1-piperazinyl)phenoxy]methyl]-7-[2-(4,4-difluorocyclohexyl)ethyl]-
CAS No.:742064-59-1
Molecular Formula:C₂₈H₃₂F₂N₆O₂
Molecular Weight:522.598
Hs Code.:

Synonyms:6-[[4-(4-acetylpiperazin-1-yl)phenoxy]methyl]-7-[2-(4,4-difluorocyclohexyl)ethyl]pyrrolo[2,3-d]pyrimidine-2-carbonitrile;7H-Pyrrolo[2,3-d]pyriMidine-2-carbonitrile, 6-[[4-(4-acetyl-1-piperazinyl)phenoxy]Methyl]-7-[2-(4,4-difluorocyclohexyl)ethyl]-

Suppliers and Price of 7H-Pyrrolo[2,3-d]pyrimidine-2-carbonitrile, 6-[[4-(4-acetyl-1-piperazinyl)phenoxy]methyl]-7-[2-(4,4-difluorocyclohexyl)ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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American Custom Chemicals Corporation
6-[[4-(4-ACETYL-1-PIPERAZINYL)PHENOXY]METHYL]-7-[2-(4,4-DIFLUOROCYCLOHEXYL)ETHYL]-7H-PYRROLO-[2,3-D]PYRIMIDINE-2-CARBONITRILE 95.00%
5MG
$ 501.59

Total 1 raw suppliers

Chemical Property of 7H-Pyrrolo[2,3-d]pyrimidine-2-carbonitrile, 6-[[4-(4-acetyl-1-piperazinyl)phenoxy]methyl]-7-[2-(4,4-difluorocyclohexyl)ethyl]-

Chemical Property:

PSA：87.28000
LogP:4.76898

Purity/Quality:: 6-[[4-(4-ACETYL-1-PIPERAZINYL)PHENOXY]METHYL]-7-[2-(4,4-DIFLUOROCYCLOHEXYL)ETHYL]-7H-PYRROLO-[2,3-D]PYRIMIDINE-2-CARBONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7H-Pyrrolo[2,3-d]pyrimidine-2-carbonitrile, 6-[[4-(4-acetyl-1-piperazinyl)phenoxy]methyl]-7-[2-(4,4-difluorocyclohexyl)ethyl]-

There total 2 articles about 7H-Pyrrolo[2,3-d]pyrimidine-2-carbonitrile, 6-[[4-(4-acetyl-1-piperazinyl)phenoxy]methyl]-7-[2-(4,4-difluorocyclohexyl)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1054314-52-1
5-{3-[-4-(4-acetylpiperazin-1-yl)phenoxy]prop-1-ynyl}-4-[2-(4,4-difluorocyclohexyl)ethylamino]pyrimidine-2-carbonitrile

: 742064-59-1
6-[4-(4-acetylpiperazin-1-yl)phenoxymethyl]-7-[2-(4,4-difluorocyclohexyl)ethyl]-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 100 ℃; for 3h; Inert atmosphere;
DOI:10.1021/jm800839j