AZD2624

Base Information

• Chemical Name: AZD2624
• CAS No.: 941690-55-7
• Molecular Formula: C₂₆H₂₅N₃O₃S
• Molecular Weight: 459.569
• Mol file: 941690-55-7.mol

Synonyms:UNII-3U471ZVC5K;AZD2624;

Chemical Property of AZD2624

Chemical Property:

• PKA: 1.35±0.30(Predicted)
• PSA: 100.03000
• Density: 1.285±0.06 g/cm3(Predicted)
• LogP: 6.88300

Purity/Quality:

97% ^*data from raw suppliers

MLE-4901 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: MLE-4901, is a neurokinin-3 receptor (NK3R) antagonist.

Technology Process of AZD2624

There total 1 articles about AZD2624 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

3-[(methylsulfonyl)amino]-2-phenylquinoline-4-carboxylic acid (941691-09-4) + (R)-1-phenylpropylamine (3789-59-1) → AZD2624 (941690-55-7)

Guidance literature:

3-[(methylsulfonyl)amino]-2-phenylquinoline-4-carboxylic acid; With 1,1'-carbonyldiimidazole; In ethyl acetate; at 50 ℃; for 6h;

(R)-1-phenylpropylamine; In ethyl acetate; at 70 ℃; for 8h;

upstream raw materials:

3-[(methylsulfonyl)amino]-2-phenylquinoline-4-carboxylic acid

(R)-1-phenylpropylamine