Ro 51

Base Information

Chemical Name:Ro 51
CAS No.:1050670-85-3
Molecular Formula:C17H23IN4O4
Molecular Weight:474.299
Hs Code.:
Mol file:1050670-85-3.mol

Synonyms:Ro 51;2-((4-Amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-yl)amino)propane-1,3-diol;2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propane-1,3-diol;2-[[4-Amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2-pyrimidinyl]amino]-1,3-propanediol;1,3-Propanediol,2-[[4-amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2-pyrimidinyl]amino]-;2-[[4-Amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinyl]amino]-1,3-propanediol

Suppliers and Price of Ro 51

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Ro 51
10mg
$ 480.00

Usbiological
Ro 51
10mg
$ 446.00

TRC
Ro51
100mg
$ 1155.00

Tocris
Ro51 ≥98%(HPLC)
50
$ 961.00

Tocris
Ro51 ≥98%(HPLC)
10
$ 229.00

Medical Isotopes, Inc.
Ro51
50 mg
$ 1100.00

Crysdot
Ro51 97%
10mg
$ 430.00

Crysdot
Ro51 97%
50mg
$ 1600.00

ApexBio Technology
Ro51
50mg
$ 1425.00

ApexBio Technology
Ro51
10mg
$ 339.00

Total 8 raw suppliers

Chemical Property of Ro 51

Chemical Property:

PSA：123.48000
LogP:2.35590

Purity/Quality:

97% ^*data from raw suppliers

Ro 51 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Ro 51 is a potent and selective dual antagonist of purinoceptor subtypes P2X3 and P2X2/3. P2X3 and P2X2/3 have been shown to play a pivotal role in models of various pain conditions making Ro 51 a pot ential option in the treatment of pain. Ro 51 is a potent and selective dual antagonist of purinoceptor subtypes P2X3 and P2X2/3. P2X3 and P2X2/3 have been shown to play a pivotal role in models of various pain conditions making Ro 51 a potential option in the treatment of pain.

Technology Process of Ro 51

There total 2 articles about Ro 51 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.8%

: 1050671-40-3
N₂-(2,2-dimethyl-[1,3]dioxan-5-yl)-5-(5-iodo-2-isopropyl-4-methoxy-phenoxy)-pyrimidine-2,4-diamine

: 1050670-85-3
RO-51

Guidance literature:: N₂-(2,2-dimethyl-[1,3]dioxan-5-yl)-5-(5-iodo-2-isopropyl-4-methoxy-phenoxy)-pyrimidine-2,4-diamine; With hydrogenchloride; water; In tetrahydrofuran; at 0 ℃; for 2h;

With sodium hydroxide; water; In tetrahydrofuran;