1-(3',4'-Dichloro-2-fluoro(1,1'-biphenyl)-4-yl)cyclopropanecarboxylic acid

Base Information

Chemical Name:1-(3',4'-Dichloro-2-fluoro(1,1'-biphenyl)-4-yl)cyclopropanecarboxylic acid
CAS No.:749269-83-8
Molecular Formula:C₁₆H₁₁Cl₂FO₂
Molecular Weight:325.167
Hs Code.:
European Community (EC) Number:633-291-3
UNII:C35RF1MWQZ
DSSTox Substance ID:DTXSID30225901
Nikkaji Number:J3.162.463K
Wikidata:Q27075958
NCI Thesaurus Code:C174649
Pharos Ligand ID:H92LM8CFVJ82
ChEMBL ID:CHEMBL196945
Mol file:749269-83-8.mol

Synonyms:1-(3',4'-dichloro-2-fluoro(1,1'-biphenyl)-4-yl)cyclopropanecarboxylic acid;CHF 5074;CHF-5074;CHF5074

Suppliers and Price of 1-(3',4'-Dichloro-2-fluoro(1,1'-biphenyl)-4-yl)cyclopropanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
CHF5074 98+%
10mg
$ 350.00

Crysdot
CHF5074 98+%
5mg
$ 245.00

Crysdot
CHF5074 98+%
100mg
$ 1470.00

Crysdot
CHF5074 98+%
50mg
$ 1050.00

ChemScene
Itanapraced >98.0%
100mg
$ 800.00

ChemScene
Itanapraced >98.0%
50mg
$ 550.00

ChemScene
Itanapraced >98.0%
5mg
$ 110.00

ChemScene
Itanapraced >98.0%
10mg
$ 160.00

Cayman Chemical
CHF5074
5mg
$ 123.00

Cayman Chemical
CHF5074
1mg
$ 29.00

Total 17 raw suppliers

Chemical Property of 1-(3',4'-Dichloro-2-fluoro(1,1'-biphenyl)-4-yl)cyclopropanecarboxylic acid

Chemical Property:

Boiling Point:466.4±45.0 °C(Predicted)
PKA:2.30±0.20(Predicted)
PSA：37.30000
Density:1.467±0.06 g/cm3(Predicted)
LogP:4.91570
Storage Temp.:2-8°C
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:324.0120131
Heavy Atom Count:21
Complexity:413

Purity/Quality:

99%, ^*data from raw suppliers

CHF5074 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,N
Hazard Codes:Xn,N
Statements: 22-50/53
Safety Statements: 60-61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1(C2=CC(=C(C=C2)C3=CC(=C(C=C3)Cl)Cl)F)C(=O)O
Recent ClinicalTrials:Safety, Pharmacokinetics and Pharmacodynamics Study of Treatment With CHF 5074 in Healthy Young Male Subjects
Recent EU Clinical Trials:A Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Tolerability of Multiple Dose Regimens of CHF 5074 (200, 400, 600 mg/day for up to 12 Weeks) and to Explore the Effects on Potential Markers of Clinical Efficacy in Patients with Mild Cognitive Impairment

Technology Process of 1-(3',4'-Dichloro-2-fluoro(1,1'-biphenyl)-4-yl)cyclopropanecarboxylic acid

There total 1 articles about 1-(3',4'-Dichloro-2-fluoro(1,1'-biphenyl)-4-yl)cyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: