4H-Imidazol-4-one, 2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5-dihydro-1,5,5-trimethyl-

Base Information

• Chemical Name: 4H-Imidazol-4-one, 2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5-dihydro-1,5,5-trimethyl-
• CAS No.: 1170700-70-5
• Molecular Formula: C22H19Cl3N4O
• Molecular Weight: 461.778
• Mol file: 1170700-70-5.mol

Synonyms:2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazol-3-yl]-1,5,5-trimethylimidazol-4-one;4H-IMidazol-4-one, 2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-Methyl-1H-pyrazol-3-yl]-1,5-dihydro-1,5,5-triMethyl-

Chemical Property of 4H-Imidazol-4-one, 2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5-dihydro-1,5,5-trimethyl-

Chemical Property:

• PSA: 50.49000
• LogP: 5.17860

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4H-Imidazol-4-one, 2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5-dihydro-1,5,5-trimethyl-

There total 2 articles about 4H-Imidazol-4-one, 2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5-dihydro-1,5,5-trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylaminoisobutyric acid amide (23232-69-1) + 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbonyl chloride (168273-05-0) → 2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydroimidazol-4-one (1170700-70-5)

Guidance literature:

2-methylaminoisobutyric acid amide; 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbonyl chloride; With triethylamine; In tetrahydrofuran; toluene; at 0 - 20 ℃;

With sodium methylate; In methanol; at 60 ℃; for 4h;

Reference yield:

C22H21Cl3N4O2 (1224836-52-5) → 2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydroimidazol-4-one (1170700-70-5)

Guidance literature:

With sodium methylate; In methanol; at 60 ℃; for 4h; Inert atmosphere;

DOI:10.1021/jm900471u

Reference yield: 77.0%

2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydroimidazol-4-one (1170700-70-5) → 2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydroimidazol-4-thione (1170700-85-2)

Guidance literature:

With Lawessons reagent; In toluene; at 60 ℃; for 4h; Inert atmosphere;

DOI:10.1021/jm900471u

upstream raw materials:

C₂₂H₂₁Cl₃N₄O₂

2-methylaminoisobutyric acid amide

5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbonyl chloride

Downstream raw materials:

2-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydroimidazol-4-thione