L-Valine, N-[[8-(2-oxo-3-oxazolidinyl)-3-dibenzofuranyl]sulfonyl]-

Base Information

Chemical Name:L-Valine, N-[[8-(2-oxo-3-oxazolidinyl)-3-dibenzofuranyl]sulfonyl]-
CAS No.:1025717-75-2
Molecular Formula:C₂₀H₂₀N₂O₇S
Molecular Weight:432.454
Hs Code.:

Synonyms:MMP145;FWPVXLYOKAOERT-SFHVURJKSA-N;L-Valine, N-[[8-(2-oxo-3-oxazolidinyl)-3-dibenzofuranyl]sulfonyl]-

Suppliers and Price of L-Valine, N-[[8-(2-oxo-3-oxazolidinyl)-3-dibenzofuranyl]sulfonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
MMP-145 95.00%
5MG
$ 500.94

Total 5 raw suppliers

Chemical Property of L-Valine, N-[[8-(2-oxo-3-oxazolidinyl)-3-dibenzofuranyl]sulfonyl]-

Chemical Property:

Boiling Point:656.9±65.0 °C(Predicted)
PSA：134.53000
Density:1.468±0.06 g/cm3(Predicted)
LogP:4.46680

Purity/Quality:

99% ^*data from raw suppliers

MMP-145 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of L-Valine, N-[[8-(2-oxo-3-oxazolidinyl)-3-dibenzofuranyl]sulfonyl]-

There total 10 articles about L-Valine, N-[[8-(2-oxo-3-oxazolidinyl)-3-dibenzofuranyl]sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1025719-35-0
(S)-3-methyl-2-[8-(2-oxo-oxazolidin-3-yl)-dibenzofuran-3-sulfonylamino]-butyric acid tert-butyl ester

: (S,E)-2-(8-((dimethylamino)methyleneamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid

: 1025717-75-2
MMP145

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;

Reference yield: 79.0%

: 1025719-35-0
(S)-3-methyl-2-[8-(2-oxo-oxazolidin-3-yl)-dibenzofuran-3-sulfonylamino]-butyric acid tert-butyl ester

: 1025717-75-2
MMP145

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm900809r

Reference yield:

: 1025719-43-0
8-bromodibenzo[b,d]furan-3-sulfonyl chloride

: 1025717-75-2
MMP145

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 18 h / 20 °C

2: sodium butanolate; tris-(o-tolyl)phosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾ / toluene / 18 h / 105 °C

3: trifluoroacetic acid / dichloromethane / 6 h / 20 °C

With N-ethyl-N,N-diisopropylamine; sodium butanolate; tris-(o-tolyl)phosphine; trifluoroacetic acid; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In dichloromethane; toluene; 1: Buchwald-Hartwig cross-coupling / 2: Buchwald-Hartwig cross-coupling;
DOI:10.1016/j.bmcl.2011.11.046