1-Piperazinecarboximidamide, N'-(3-bromophenyl)-N-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (2S)-

Base Information

Chemical Name:1-Piperazinecarboximidamide, N'-(3-bromophenyl)-N-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (2S)-
CAS No.:1116571-01-7
Molecular Formula:C20H21BrN8
Molecular Weight:453.344
Hs Code.:
Mol file:1116571-01-7.mol

Synonyms:

Suppliers and Price of 1-Piperazinecarboximidamide, N'-(3-bromophenyl)-N-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-Piperazinecarboximidamide, N'-(3-bromophenyl)-N-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (2S)-

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Piperazinecarboximidamide, N'-(3-bromophenyl)-N-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (2S)-

There total 2 articles about 1-Piperazinecarboximidamide, N'-(3-bromophenyl)-N-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 853763-68-5
phenyl N-(3-bromophenyl)-N'-cyanoimidocarbamate

: 1116570-96-7
(S)-5-methyl-4-(3-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine

: 1116571-01-7
(S)-N-(3-bromophenyl)-N'-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazine-1-carboximidamide

Guidance literature:: With triethylamine; In acetonitrile; for 2h; Inert atmosphere; Reflux;
DOI:10.1021/jm901226j

Reference yield: 57.0%

: 853763-68-5
phenyl N-(3-bromophenyl)-N'-cyanoimidocarbamate

: 1116570-96-7
(S)-5-methyl-4-(3-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine

: 1116571-01-7
(S)-N-(3-bromophenyl)-N'-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazine-1-carboximidamide

Guidance literature:: phenyl N-(3-bromophenyl)-N'-cyanoimidocarbamate; (S)-5-methyl-4-(3-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine; With triethylamine; In acetonitrile; at 85 ℃; for 6h;

With water; In methanol;