5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)oxazole

Base Information

Chemical Name:5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)oxazole
CAS No.:942070-84-0
Molecular Formula:C9H14BNO3
Molecular Weight:195.026
Hs Code.:2934999090
DSSTox Substance ID:DTXSID50699448
Wikidata:Q82630374
Mol file:942070-84-0.mol

Synonyms:942070-84-0;5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)OXAZOLE;5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole;5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-oxazole;SCHEMBL120878;5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-oxazole;DTXSID50699448;MFCD12405501;Oxazole-5-boronic acid pinacol ester;AB65539;AS-83377;1,3-Oxazol-5-ylboronic acid pinacol ester;CS-0094554;FT-0731749;OXAZOL-5-YLBORONIC ACID PINACOL ESTER;P19499;A901214

Suppliers and Price of 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole
25mg
$ 225.00

TRC
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole
10mg
$ 140.00

JR MediChem
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole 96%
10g
$ 7180.00

JR MediChem
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole 96%
5g
$ 4280.00

JR MediChem
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole 96%
1g
$ 1480.00

J&W Pharmlab
5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole 96%
250mg
$ 325.00

J&W Pharmlab
5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole 96%
100mg
$ 218.00

J&W Pharmlab
5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole 96%
50mg
$ 159.00

J&W Pharmlab
5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole 96%
500mg
$ 549.00

J&W Pharmlab
5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-oxazole 96%
1g
$ 998.00

Total 16 raw suppliers

Chemical Property of 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)oxazole

Chemical Property:

Boiling Point:276.7±13.0 °C(Predicted)
PKA:0.58±0.10(Predicted)
PSA：44.49000
Density:1.08±0.1 g/cm3(Predicted)
LogP:0.97380
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:195.1066735
Heavy Atom Count:14
Complexity:216

Purity/Quality:

97% ^*data from raw suppliers

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CN=CO2
Uses 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole is a reagent used in the preparation of checkpoint kinase I (Chk1) inhibitors, used in the treatment of DNA damage and facilitating cell-cycle arrest.

Technology Process of 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)oxazole

There total 1 articles about 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 942070-84-0
5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)oxazole

Guidance literature:

Reference yield: 100.0%

: 942070-84-0
5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)oxazole

: 1041861-97-5
4-(2-chloro-pyridin-4-yloxy)-2-fluorophenylamine

: 1070162-80-9
2-fluoro-4-(2-(oxazol-5-yl)pyridin-4-yloxy)benzenamine

Guidance literature:: With caesium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; N,N-dimethyl-formamide; at 80 ℃;

Reference yield: 44.0%

: 942070-84-0
5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)oxazole

: rac-tert-butyl {1-[({6-bromo-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridin-3-yl}carbonyl)amino]-2-methylbutan-2-yl}carbamate

: rac-tert-butyl {1-[({8-[(2,6-difluorobenzyl)oxy]-2-methyl-6-(1,3-oxazol-5-yl)imidazo[1,2-a]pyridin-3-yl}carbonyl)amino]-2-methylbutan-2-yl}carbamate

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; caesium carbonate; In 1,4-dioxane; water; at 100 ℃; for 2h; Inert atmosphere; Sealed tube;