1-BroMo-3-[3-(trifluoroMethyl)phenyl]propane

Base Information

Chemical Name:1-BroMo-3-[3-(trifluoroMethyl)phenyl]propane
CAS No.:129254-76-8
Molecular Formula:C10H10BrF3
Molecular Weight:267.089
Hs Code.:
Mol file:129254-76-8.mol

Synonyms:1-Bromo-3-[3-(trifluoromethyl)phenyl]propane;

Suppliers and Price of 1-BroMo-3-[3-(trifluoroMethyl)phenyl]propane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(3-Bromopropyl)-3-(trifluoromethyl)benzene
500mg
$ 345.00

Chemenu
1-(3-bromopropyl)-3-(trifluoromethyl)benzene 95%+
10g
$ 937.00

American Custom Chemicals Corporation
1-(3-BROMOPROPYL)-3-(TRIFLUOROMETHYL)BENZENE 95.00%
5MG
$ 495.15

AK Scientific
1-(3-Bromopropyl)-3-(trifluoromethyl)benzene
500mg
$ 684.00

AK Scientific
1-(3-Bromopropyl)-3-(trifluoromethyl)benzene
100mg
$ 313.00

Acrotein
1-(3-Bromopropyl)-3-(trifluoromethyl)benzene 97%
1g
$ 275.00

ACHEMBLOCK
1-(3-Bromopropyl)-3-(trifluoromethyl)benzene 95%
5G
$ 975.00

ACHEMBLOCK
1-(3-Bromopropyl)-3-(trifluoromethyl)benzene 95%
1G
$ 365.00

Total 19 raw suppliers

Chemical Property of 1-BroMo-3-[3-(trifluoroMethyl)phenyl]propane

Chemical Property:

Boiling Point:226.3 °C at 760 mmHg
Flash Point:106 °C
PSA：0.00000
Density:1.44 g/cm³
LogP:4.03290
Storage Temp.:Refrigerator, under inert atmosphere
Solubility.:Chloroform (Sparingly), Ethyl Acetate (Slightly)

Purity/Quality:

99% ,98%,Electron Grade , ^*data from raw suppliers

1-(3-Bromopropyl)-3-(trifluoromethyl)benzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-(3-Bromopropyl)-3-(trifluoromethyl)benzene is a key intermediate in the synthesis of Cinacalcet Hydrochloride (C441800). Cinacalcet Hydrochloride is the (R) enantiomer of Cinacalcet and is used in clinical trial in secondary hyperparathyroidism.

Technology Process of 1-BroMo-3-[3-(trifluoroMethyl)phenyl]propane

There total 8 articles about 1-BroMo-3-[3-(trifluoroMethyl)phenyl]propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.97%

: 78573-45-2
3-[3-(trifluoromethyl)phenyl]propan-1-ol

: 129254-76-8
1-(3-bromopropyl)-3- (trifluoromethyl)benzene

Guidance literature:: With sulfuric acid; hydrogen bromide; tetra(n-butyl)ammonium hydrogensulfate; In water; at 82 ℃; for 25h; Temperature; Concentration; Reagent/catalyst;

Reference yield: 76.45%

: 78573-45-2
3-[3-(trifluoromethyl)phenyl]propan-1-ol

: 1-[(1E)-3-bromopropyl-1-en-1-yl]-3-(trifluoromethyl)benzene

: 129254-76-8
1-(3-bromopropyl)-3- (trifluoromethyl)benzene

Guidance literature:: With sulfuric acid; hydrogen bromide; In water; at 25 - 55 ℃;
DOI:10.1021/op200016a

Reference yield: 53.0%

: 1-Cyclopropyl-3-trifluoromethyl-benzene

: 129254-76-8
1-(3-bromopropyl)-3- (trifluoromethyl)benzene

Guidance literature:: With boron tribromide; tert-butyl alcohol; In dichloromethane; at 23 ℃; for 44h; regioselective reaction;
DOI:10.1039/d0sc02567d