pyrazine-2,5-dicarbaldehyde

Base Information

• Chemical Name: pyrazine-2,5-dicarbaldehyde
• CAS No.: 77666-94-5
• Molecular Formula: C6H4N2O2
• Molecular Weight: 136.11
• Mol file: 77666-94-5.mol

Synonyms:Pyrazine-2,5-dicarbaldehyde;

Chemical Property of pyrazine-2,5-dicarbaldehyde

Chemical Property:

• Melting Point: 124-125 °C(Solv: chloroform (67-66-3); isopropyl ether (108-20-3))
• Boiling Point: 273.833 °C at 760 mmHg
• PKA: -3.28±0.10(Predicted)
• Flash Point: 123.552 °C
• PSA: 59.92000
• Density: 1.372 g/cm³
• LogP: 0.10160

Purity/Quality:

98%min ^*data from raw suppliers

Pyrazine-2,5-dicarbaldehyde 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of pyrazine-2,5-dicarbaldehyde

There total 9 articles about pyrazine-2,5-dicarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,5-bis(hydroxymethyl)pyrazine (79068-45-4) → 2,5-pyrazine-dicarboxaldehyde (77666-94-5)

Guidance literature:

With manganese(IV) oxide; In 1,4-dioxane; at 96 ℃; for 0.75h; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.05.057

Reference yield: 49.0%

2,5-distyrylpyrazine (14990-02-4) → 2,5-pyrazine-dicarboxaldehyde (77666-94-5)

Guidance literature:

2,5-distyrylpyrazine; With ozone; In methanol;

With sodium metabisulfite;

DOI:10.1007/s10847-019-00904-y

Reference yield: 30.0%

2,5-(E,E)-distyrylpyrazine (21899-24-1,14990-02-4) → 2,5-pyrazine-dicarboxaldehyde (77666-94-5)

Guidance literature:

2,5-(E,E)-distyrylpyrazine; With ozone; In methanol; at -78 ℃;

With sodium metabisulfite; In methanol;

DOI:10.1002/chem.200401261

upstream raw materials:

2,5-dimethyl-pyrazine

2,5-(E,E)-distyrylpyrazine

2,5-distyrylpyrazine

2,5-bis(hydroxymethyl)pyrazine

Refernces

• 1、 Dais, Tyson N.,Brown, Michael J.,Coles, Martyn P.,Laur, Fran?ois,Price, Jason R.,Rowlands, Gareth J.,Plieger, Paul G.. "Synthesis and characterization of Co(II) and Mn(II) [M3L3] triangles". . p. 175 - 182. Retrieved 2019/07/16.
• 2、 Li, Jiu-Long,Chai, Yun-Fei,Wang, Wei Vanessa,Shi, Zi-Fa,Xu, Zhu-Guo,Zhang, Hao-Li. "Pyrazine-fused isoindigo: A new building block for polymer solar cells with high open circuit voltage". supporting information. p. 5882 - 5885. Retrieved 2017/07/11.