1H-Pyrrolo[2,3-b]pyridin-3-amine, 5-chloro-2-methyl-

Base Information

Chemical Name:1H-Pyrrolo[2,3-b]pyridin-3-amine, 5-chloro-2-methyl-
CAS No.:936243-42-4
Molecular Formula:C₈H₈ClN₃
Molecular Weight:181.625
Hs Code.:
Mol file:936243-42-4.mol

Synonyms:5-Chloro-2-methylisothiazolidin-3-one;5-chloro-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-ylamine;5-chloro-2-methyl-3-isothiazolidinone;

Suppliers and Price of 1H-Pyrrolo[2,3-b]pyridin-3-amine, 5-chloro-2-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
5-chloro-2-methyl-1H-Pyrrolo[2,3-b]pyridin-3-amine 97.00%
25G
$ 8510.00

AccelPharmtech
5-chloro-2-methyl-1H-Pyrrolo[2,3-b]pyridin-3-amine 97.00%
5G
$ 4530.00

AccelPharmtech
5-chloro-2-methyl-1H-Pyrrolo[2,3-b]pyridin-3-amine 97.00%
1G
$ 2640.00

Total 2 raw suppliers

Chemical Property of 1H-Pyrrolo[2,3-b]pyridin-3-amine, 5-chloro-2-methyl-

Chemical Property:

PSA：54.70000
LogP:2.68810

Purity/Quality:

99% ^*data from raw suppliers

5-chloro-2-methyl-1H-Pyrrolo[2,3-b]pyridin-3-amine 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrolo[2,3-b]pyridin-3-amine, 5-chloro-2-methyl-

There total 2 articles about 1H-Pyrrolo[2,3-b]pyridin-3-amine, 5-chloro-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 936243-20-8
5-chloro-2-methyl-3-nitroso-1H-pyrrolo[2,3-b]pyridine

: 936243-42-4
5-chloro-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-ylamine

Guidance literature:: With sodium hydroxide; sodium dithionite; ethanol; for 0.5h; Heating;
DOI:10.1016/j.bmc.2007.02.029

Reference yield:

: 145934-81-2
5-chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine

: 936243-42-4
5-chloro-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / acetic acid; sodium nitrite / H₂O / 0.5 h / 20 °C

2: 67 percent / sodium dithionite; sodium hydroxide; ethanol / 0.5 h / Heating

With sodium hydroxide; sodium dithionite; ethanol; acetic acid; sodium nitrite; In water;
DOI:10.1016/j.bmc.2007.02.029