6-Methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine

Base Information

• Chemical Name: 6-Methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine
• CAS No.: 1092394-15-4
• Molecular Formula: C7H8N4O
• Molecular Weight: 164.16
• Hs Code.: 2933990090
• Mol file: 1092394-15-4.mol

Synonyms:6-Methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine

Chemical Property of 6-Methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine

Chemical Property:

• PSA: 66.17000
• Density: 1.482 g/cm³
• LogP: 0.25020

Purity/Quality:

98%min ^*data from raw suppliers

6-Methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine

There total 5 articles about 6-Methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

ethyl [(5-methoxypyridin-2-yl)carbamothioyl]carbamate → 6-methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine (1092394-15-4)

Guidance literature:

With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine; In methanol; ethanol; at 80 ℃; for 8h;

Reference yield: 92.0%

→ 6-methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine (1092394-15-4)

Guidance literature:

Reference yield: 83.0%

ethyl {[(5-methoxypyridin-2-yl)amino]carbonothioyl}carbamate (1092394-14-3) → 6-methoxy-[1,2,4]triazolo[1,5-a]pyridin-2-amine (1092394-15-4)

Guidance literature:

With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine; In methanol; ethanol; at 20 - 60 ℃; for 6h;

upstream raw materials:

ethyl {[(5-methoxypyridin-2-yl)amino]carbonothioyl}carbamate

2-amino-5-methoxypyridine

Downstream raw materials:

N-[6-(2-fluoro-4-nitrophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

N-[6-(4-amino-2-fluorophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

N-[3-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-5-fluorophenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide

N-[6-(3-fluoro-5-nitrophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

Refernces

• 1、 -. "QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS". . . Retrieved 2011/05/11.
• 2、 -. "FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF". Page/Page column 161-162. . Retrieved 2010/01/29.