5-Hydroxy-1H-indazole-3-carbaldehyde

Base Information

Chemical Name:5-Hydroxy-1H-indazole-3-carbaldehyde
CAS No.:882803-11-4
Molecular Formula:C₈H₆N₂O₂
Molecular Weight:162.148
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30434071
Wikidata:Q82248387
Mol file:882803-11-4.mol

Synonyms:882803-11-4;5-Hydroxy-1H-indazole-3-carbaldehyde;5-Hydroxy-3-(1H)indazole carboxaldehyde;5-hydroxy-1H-Indazole-3-carboxaldehyde;5-hydroxy-2H-indazole-3-carbaldehyde;SCHEMBL3538836;DTXSID30434071;MFCD07781438;AKOS005258961;5-Hydroxy-3-(1H)indazolecarboxaldehyde;5-Hydroxy-3-(1H)-indazole carbaldehyde;AC-25002;CS-0360790;FT-0761672

Suppliers and Price of 5-Hydroxy-1H-indazole-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Hydroxy-3-(1H)indazolecarboxaldehyde 95+%
1g
$ 772.00

Chemenu
5-hydroxy-1H-indazole-3-carbaldehyde 95%
1g
$ 729.00

American Custom Chemicals Corporation
5-HYDROXY-1H-INDAZOLE-3-CARBOXALDEHYDE 95.00%
5MG
$ 496.89

Alichem
5-Hydroxy-3-(1H)indazolecarboxaldehyde
10g
$ 4192.65

Alichem
5-Hydroxy-3-(1H)indazolecarboxaldehyde
5g
$ 2680.00

Total 10 raw suppliers

Chemical Property of 5-Hydroxy-1H-indazole-3-carbaldehyde

Chemical Property:

Boiling Point:451.0±25.0 °C(Predicted)
PKA:8.12±0.40(Predicted)
PSA：65.98000
Density:1.541±0.06 g/cm3(Predicted)
LogP:1.08100
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:162.042927438
Heavy Atom Count:12
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

5-Hydroxy-3-(1H)indazolecarboxaldehyde 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NNC(=C2C=C1O)C=O

Technology Process of 5-Hydroxy-1H-indazole-3-carbaldehyde

There total 7 articles about 5-Hydroxy-1H-indazole-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 169789-37-1
5-methoxy-1H-indazole-3-carboxaldehyde

: 882803-11-4
5-hydroxy-1H-indazole-3-carbaldehyde

Guidance literature:: With boron tribromide; In dichloromethane; for 3h; Ambient temperature;
DOI:10.1021/jm00013a010

Reference yield:

: 1346152-69-9
3-formyl-1H-indazol-5-yl acetate

: 882803-11-4
5-hydroxy-1H-indazole-3-carbaldehyde

Guidance literature:: With methanol; potassium carbonate; at 20 ℃; for 0.5h;

Reference yield:

: 94444-96-9
5-methoxy-1H-indazole

: 882803-11-4
5-hydroxy-1H-indazole-3-carbaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 35 percent / K₂CO₃ / 4 h / 270 °C / 52504.2 Torr

2: 68 percent / LiAlH₄ / tetrahydrofuran / 3 h / 50 °C

3: 83 percent / MnO₂ / tetrahydrofuran; CH₂Cl₂ / Ambient temperature

4: 95 percent / boron tribromide / CH₂Cl₂ / 3 h / Ambient temperature

With manganese(IV) oxide; lithium aluminium tetrahydride; boron tribromide; potassium carbonate; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00013a010