2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole

Base Information

Chemical Name:2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole
CAS No.:1229000-10-5
Molecular Formula:C17H23N3O2
Molecular Weight:301.38342
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10682159
Mol file:1229000-10-5.mol

Synonyms:1229000-10-5;2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole;TERT-BUTYL 3-(1H-BENZO[D]IMIDAZOL-2-YL)PIPERIDINE-1-CARBOXYLATE;tert-Butyl 3-(1H-benzimidazol-2-yl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 3-(1H-benzimidazol-2-yl)-, 1,1-dimethylethyl ester;SCHEMBL739188;SCHEMBL19408169;DTXSID10682159;NQJXCURWALTMNK-UHFFFAOYSA-N;CS-B0085;tert-butyl 3-(1H-1,3-benzodiazol-2-yl)piperidine-1-carboxylate;MFCD17214278;AKOS015854405;DS-1038;A890879

Suppliers and Price of 2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole
100mg
$ 90.00

TRC
2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole
50mg
$ 65.00

Matrix Scientific
2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole 95+%
5g
$ 1607.00

Matrix Scientific
2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole 95+%
1g
$ 599.00

Matrix Scientific
2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole 95+%
250mg
$ 278.00

Crysdot
2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole 95+%
5g
$ 451.00

Chemenu
2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole 95%
5g
$ 262.00

American Custom Chemicals Corporation
2-(N-BOC-PIPERIDIN-3-YL)-1H-BENZOIMIDAZOLE 95.00%
5MG
$ 504.16

Ambeed
2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole 96%
1g
$ 58.00

Ambeed
2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole 96%
250mg
$ 23.00

Total 30 raw suppliers

Chemical Property of 2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole

Chemical Property:

PSA：58.22000
LogP:3.61530
Storage Temp.:Room temperature.
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:301.17902698
Heavy Atom Count:22
Complexity:407

Purity/Quality:

99%, ^*data from raw suppliers

2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC(C1)C2=NC3=CC=CC=C3N2
Uses 2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole is used as a reactant in the synthesis of piperidinyl benzimidazoles as CNS penetrating H1-antihistamines.

Technology Process of 2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole

There total 5 articles about 2-(N-Boc-piperidin-3-yl)-1H-benzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 71381-75-4,88495-54-9,84358-12-3
N-(tert-butyloxycarbonyl)nipecotic acid

: 95-54-5
1,2-diamino-benzene

: 1229000-10-5
tert-butyl 3-(1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate

Guidance literature:: at 120 ℃; neat (no solvent);
DOI:10.1016/j.bmcl.2010.03.027

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1443057-91-7
tert-butyl 3-((2-aminophenyl)carbamoyl)piperidine-1-carboxylate

: 1229000-10-5
tert-butyl 3-(1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate

Guidance literature:: tert-butyl 3-((2-aminophenyl)carbamoyl)piperidine-1-carboxylate; With hydrogenchloride; In water; at 50 - 60 ℃; for 3h;

di-tert-butyl dicarbonate; With triethylamine; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;