2-(4-Chloro-1H-indol-3-yl)ethanol, N-BOC protected

Base Information

Chemical Name:2-(4-Chloro-1H-indol-3-yl)ethanol, N-BOC protected
CAS No.:898746-54-8
Molecular Formula:C₁₅H₁₈ClNO₃
Molecular Weight:295.766
Hs Code.:2933990090
Mol file:898746-54-8.mol

Synonyms:2-(4-Chloro-1H-indol-3-yl)ethanol, N-BOC protected;tert-butyl 4-chloro-3-(2-hydroxyethyl)-1H-indole-1-carboxylate

Suppliers and Price of 2-(4-Chloro-1H-indol-3-yl)ethanol, N-BOC protected

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl4-chloro-3-(2-hydroxyethyl)-1H-indole-1-carboxylate 95+%
1g
$ 455.00

Chemenu
tert-Butyl4-chloro-3-(2-hydroxyethyl)-1H-indole-1-carboxylate 95%
1g
$ 430.00

American Custom Chemicals Corporation
2-(4-CHLORO-1H-INDOL-3-YL)ETHANOL, N-BOC PROTECTED 95.00%
25G
$ 2037.42

Alichem
tert-Butyl4-chloro-3-(2-hydroxyethyl)-1H-indole-1-carboxylate
1g
$ 401.76

Total 15 raw suppliers

Chemical Property of 2-(4-Chloro-1H-indol-3-yl)ethanol, N-BOC protected

Chemical Property:

PSA：51.46000
LogP:3.61270
Storage Temp.:2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

tert-Butyl4-chloro-3-(2-hydroxyethyl)-1H-indole-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(4-Chloro-1H-indol-3-yl)ethanol, N-BOC protected

There total 3 articles about 2-(4-Chloro-1H-indol-3-yl)ethanol, N-BOC protected which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: C₂₁H₃₂ClNO₃Si

: 898746-54-8
tert-butyl 4-chloro-3-(2-hydroxyethyl)-1H-indole-1-carboxylate

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 5h;
DOI:10.1055/a-1310-5213

Reference yield:

: 41340-30-1
2-(4-chloro-indol-3-yl)-ethanol

: 898746-54-8
tert-butyl 4-chloro-3-(2-hydroxyethyl)-1H-indole-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 4.5 h / 0 - 20 °C

2: dmap / dichloromethane / 2 h / 20 °C

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 0 - 20 °C

With 1H-imidazole; dmap; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/a-1310-5213

Reference yield:

: C₁₆H₂₄ClNOSi

: 898746-54-8
tert-butyl 4-chloro-3-(2-hydroxyethyl)-1H-indole-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / dichloromethane / 2 h / 20 °C

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 0 - 20 °C

With dmap; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane;
DOI:10.1055/a-1310-5213