3-Bromo-4-iodobenzoic acid

Base Information

• Chemical Name: 3-Bromo-4-iodobenzoic acid
• CAS No.: 249647-25-4
• Molecular Formula: C7H4BrIO2
• Molecular Weight: 326.916
• Hs Code.: 2916399090
• Mol file: 249647-25-4.mol

Synonyms:3-bromo-4-iodobenzoic acid

Chemical Property of 3-Bromo-4-iodobenzoic acid

Chemical Property:

• Melting Point: 242-243℃
• PSA: 37.30000
• LogP: 2.75190
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

3-Bromo-4-iodobenzoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Bromo-4-iodobenzoic acid

There total 12 articles about 3-Bromo-4-iodobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

→ 3-bromo-4-iodobenzoic acid (249647-25-4)

Guidance literature:

Reference yield: 84.0%

3-bromo-4-iodobenzoic acid methyl ester (249647-24-3) → 3-bromo-4-iodobenzoic acid (249647-25-4)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1021/jm990229t

Reference yield: 75.0%

4-iodobenzoic acid (619-58-9) → 3-bromo-4-iodobenzoic acid (249647-25-4)

Guidance literature:

With N-Bromosuccinimide; sulfuric acid; at 20 ℃;

DOI:10.1002/chem.201404498

upstream raw materials:

3-bromo-4-iodobenzaldehyde

2-bromo-4-ethyl-1-iodobenzene

3-bromo-4-iodobenzoic acid methyl ester

methyl 4-iodobenzoate

Downstream raw materials:

(3-bromo-4-iodophenyl)methanol

tert-butyl 3-bromo-4-iodobenzoate

C₂₂H₂₄Br₂O₄S₂

tert-butyl 3-bromo-4-((phenylsulfonyl)thio)benzoate

Refernces

• 1、 Kunz, Thomas,Knochel, Paul. "Synthesis of functionalized benzo[b]thiophenes by the intramolecular copper-catalyzed carbomagnesiation of alkynyl(aryl)thioethers". . p. 1958 - 1961. Retrieved 2012/04/18.
• 2、 -. "BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 066". Page/Page column 157. . Retrieved 2009/06/27.