N2-Benzyloxycarbonyl-L-homoglutamine

Base Information

• Chemical Name: N2-Benzyloxycarbonyl-L-homoglutamine
• CAS No.: 83793-19-5
• Molecular Formula: C₁₄H₁₈N₂O₅
• Molecular Weight: 294.307
• DSSTox Substance ID: DTXSID40551703
• Wikidata: Q82431505
• Mol file: 83793-19-5.mol

Synonyms:N2-Benzyloxycarbonyl-L-homoglutamine;83793-19-5;(2S)-6-amino-6-oxo-2-(phenylmethoxycarbonylamino)hexanoic acid;N2-Cbz-L-homoglutamine;N~2~-[(Benzyloxy)carbonyl]-6-oxo-L-lysine;DTXSID40551703;AKOS007930196;(2S)-5-(Aminocarbonyl)-NZ-2-aminopentanoic acid;(2S)-2-{[(BENZYLOXY)CARBONYL]AMINO}-5-CARBAMOYLPENTANOIC ACID

Chemical Property of N2-Benzyloxycarbonyl-L-homoglutamine

Chemical Property:

• PSA: 123.20000
• LogP: 2.37570
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 9
• Exact Mass: 294.12157168
• Heavy Atom Count: 21
• Complexity: 366

Purity/Quality:

99% ^*data from raw suppliers

N2-Benzyloxycarbonyl-L-homoglutamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC(=O)NC(CCCC(=O)N)C(=O)O
• Isomeric SMILES: C1=CC=C(C=C1)COC(=O)N[C@@H](CCCC(=O)N)C(=O)O
• Uses: Protected L-homoglutamine.

Technology Process of N2-Benzyloxycarbonyl-L-homoglutamine

There total 4 articles about N2-Benzyloxycarbonyl-L-homoglutamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)-2-benzyloxycarbonylamino-adipic acid diamide (24325-19-7) → L-2-benzyloxycarbonylamino-adipamic acid (83793-19-5)

Guidance literature:

With papain-substance; DL-cysteine hydrochloride; at 37 ℃;

Reference yield:

→ (+/-)-2-benzyloxycarbonylamino-adipamic acid (83793-19-5)

Guidance literature:

With ammonium hydroxide;

Reference yield:

(R,S)-2-aminoadipic acid (542-32-5) → L-2-benzyloxycarbonylamino-adipamic acid (83793-19-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanolic HCl / Behandeln des erhaltenen Diaethylesters mit Chlorokohlensaeure-benzylester und MgO in H₂O und CHCl₃ und Behandeln des Reaktionsprodukts mit methanol. NH₃

2: cysteine-hydrochloride; papain-substance; aqueous solution of pH 5 / 37 °C

With hydrogenchloride; papain-substance; DL-cysteine hydrochloride;

upstream raw materials:

(+/-)-2-benzyloxycarbonylamino-adipic acid diamide

(R,S)-2-aminoadipic acid

Downstream raw materials:

(+/-)-2-amino-adipamic acid