(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one

Base Information

Chemical Name:(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one
CAS No.:847926-88-9
Molecular Formula:C₁₄H₁₂N₂O
Molecular Weight:224.262
Hs Code.:
Mol file:847926-88-9.mol

Synonyms:(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one ;(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one-11;(S)-7-amino-5,7-dihydro-6H-dibenzo[b,d]azepin-6-one;6H-Dibenz[b,d]azepin-6-one, 7-amino-5,7-dihydro-, (7S)-

Suppliers and Price of (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one
1mg
$ 95.00

TRC
(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one
25mg
$ 1390.00

American Custom Chemicals Corporation
(S)-7-AMINO-5H-7H-DIBENZO[B,D]AZEPIN-6-ONE 95.00%
10MG
$ 367.50

Total 7 raw suppliers

Chemical Property of (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one

Chemical Property:

PSA：58.61000
LogP:3.09090
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A building block for γ-secretase inhibitors for treatment of Alzheimer's disease. Several γ-secretase inhibitors have been described that contain (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one.

Technology Process of (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one

There total 11 articles about (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 847926-46-9
(S)-7-amino-5-(4-methoxy-benzyl)-5H,7H-dibenzo[b,d]azepin-6-one

: 847926-88-9
(S)-7-amino-5H-dibenzo[b,d]azepin-6(7H)-one

Guidance literature:: With trifluorormethanesulfonic acid; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;

Reference yield: 94.0%

: [(S)-5-(4-methoxy-benzyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-carbamic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

: 847926-88-9
(S)-7-amino-5H-dibenzo[b,d]azepin-6(7H)-one

Guidance literature:: [(S)-5-(4-methoxy-benzyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-carbamic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester; With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 0.25h;

With trifluorormethanesulfonic acid; In dichloromethane; at 20 ℃; for 16.25h;

With sodium hydrogencarbonate; In dichloromethane; water;