N-(ε-N-Benzyloxycarbonylamino)caproyl)-β-D-galactopyranosylamine (contains approx 35% Ethanol)

Base Information

• Chemical Name: N-(ε-N-Benzyloxycarbonylamino)caproyl)-β-D-galactopyranosylamine (contains approx 35% Ethanol)
• CAS No.: 38822-58-1
• Molecular Formula: C₂₀H₃₀N₂O₈
• Molecular Weight: 426.467
• Mol file: 38822-58-1.mol

Synonyms:N-N-Benzyloxycarbonyl-|A-aminocaproyl-|A-D-galactopyranosylamine;

Chemical Property of N-(ε-N-Benzyloxycarbonylamino)caproyl)-β-D-galactopyranosylamine (contains approx 35% Ethanol)

Chemical Property:

• Melting Point: 130-133 C
• PSA: 164.56000
• LogP: 0.43400
• Solubility.: DMSO, Warm Ethanol, Methanol, Warm Water

Purity/Quality:

95% ^*data from raw suppliers

N-(ε-N-Benzyloxycarbonylamino)caproyl)-β-D-galactopyranosylamine(containsapprox35%Ethanol) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-(ε-N-Benzyloxycarbonylamino)caproyl)-β-D-galactopyranosylamine (contains approx 35% Ethanol) is used for the preparation of sugar specific antibodies using liposomes.

Technology Process of N-(ε-N-Benzyloxycarbonylamino)caproyl)-β-D-galactopyranosylamine (contains approx 35% Ethanol)

There total 6 articles about N-(ε-N-Benzyloxycarbonylamino)caproyl)-β-D-galactopyranosylamine (contains approx 35% Ethanol) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

β-D-mannopyranosyl amine (7388-99-0,50444-86-5) + 6-(benzyloxycarbonylamino)hexanoic acid (1947-00-8) → N-<(6-benzyloxycarbonylamino)hexanoyl>-β-D-mannopyranosylamine (74761-71-0,38822-58-1)

Guidance literature:

for 20h;

DOI:10.1016/S0008-6215(00)80796-X

Reference yield:

D-Mannose pentaacetate (83-87-4,604-68-2,604-69-3,2152-77-4,4026-35-1,4163-59-1,4163-60-4,4163-61-5,4163-65-9,4257-94-7,4257-96-9,16299-15-3,19186-39-1,19189-55-0,25878-60-8,25941-03-1,32445-48-0,32445-49-1,32445-53-7,32445-54-8,34685-58-0,34685-59-1,43168-42-9,43168-44-1,43169-22-8,43169-25-1,66966-07-2,70749-17-6,80184-01-6,93221-01-3,93221-02-4,99630-88-3,109215-53-4,115792-70-6,115792-73-9,139894-92-1,139973-25-4,144071-49-8,147648-81-5) → N-<(6-benzyloxycarbonylamino)hexanoyl>-β-D-mannopyranosylamine (74761-71-0,38822-58-1)

Guidance literature:

Multi-step reaction with 4 steps

1: stannic tetrachloride / CH₂Cl₂ / 6 h

2: 61 percent / H₂ / Raney nickel / ethyl acetate / 6.5 h

3: 58 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 1 h / Ambient temperature

4: sodium methoxide / methanol / 2 h

With dmap; hydrogen; sodium methylate; tin(IV) chloride; nickel; In methanol; dichloromethane; ethyl acetate;

DOI:10.1016/S0008-6215(00)85529-9

Reference yield:

2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl azide (53784-29-5) → N-<(6-benzyloxycarbonylamino)hexanoyl>-β-D-mannopyranosylamine (74761-71-0,38822-58-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 61 percent / H₂ / Raney nickel / ethyl acetate / 6.5 h

2: 58 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 1 h / Ambient temperature

3: sodium methoxide / methanol / 2 h

With dmap; hydrogen; sodium methylate; nickel; In methanol; dichloromethane; ethyl acetate;

DOI:10.1016/S0008-6215(00)85529-9

upstream raw materials:

β-D-mannopyranosyl amine

6-(benzyloxycarbonylamino)hexanoic acid

2,3,4,6-tetra-O-acetyl-N-<(6-benzyloxycarbonylamino)hexanoyl>-β-D-mannopyranosylamine

D-Mannose pentaacetate