(+/-)-NFPS HYDROCHLORIDE

Base Information

• Chemical Name: (+/-)-NFPS HYDROCHLORIDE
• CAS No.: 200006-08-2
• Molecular Formula: C24H25ClFNO3
• Molecular Weight: 429.91
• Mol file: 200006-08-2.mol

Synonyms:ALX 5407 HYDROCHLORIDE;N-[3-(4'-FLUOROPHENYL)-3-(4'-PHENYLPHENOXY)PROPYL]SARCOSINE HYDROCHLORIDE;(±)-NFPS hydrochloride, N-[3-(4μ-Fluorophenyl)-3-(4μ-phenylphenoxy)propyl]sarcosine hydrochloride;

Chemical Property of (+/-)-NFPS HYDROCHLORIDE

Chemical Property:

• PSA: 49.77000
• LogP: 5.82130
• Storage Temp.: 2-8°C
• Solubility.: DMSO: ~16 mg/mL, soluble

Purity/Quality:

98%,99%, ^*data from raw suppliers

NFPS hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N
• Hazard Codes: Xn,N
• Statements: 22-50/53
• Safety Statements: 22-24/25-61-60

MSDS Files:

SDS file from LookChem

Useful:

• Uses: ALX 5407 Hydrochloride can be used in the preparation of amino acid derivatives as pharmaceuticals for treatment of neurological and neuropsychiatric disorders. ALX 5407 hydrochloride has been used as a glycine transporter (GlyT1) inhibitor to test its effect on inhibitory postsynaptic current and N-methyl-D-aspartate receptor (NMDA)-mediated excitatory postsynaptic currents (EPSCs). It has also been used as a GlyT1 inhibitor to treat developmentally diminished NMDA receptor (Grin1D481N) mice to test its effect on the glycine site function.