[4-(5-Oxazolyl)phenyl]methanol

Base Information

• Chemical Name: [4-(5-Oxazolyl)phenyl]methanol
• CAS No.: 179057-18-2
• Molecular Formula: C10H9NO2
• Molecular Weight: 175.187
• Hs Code.: 2934999090
• Mol file: 179057-18-2.mol

Synonyms:[4-(5-Oxazolyl)phenyl]Methanol;[4-(1,3-Oxazol-5-yl)phenyl]methanol, 4-(1,3-Oxazol-5-yl)benzyl alcohol

Chemical Property of [4-(5-Oxazolyl)phenyl]methanol

Chemical Property:

• Melting Point: 107～109℃
• PSA: 46.26000
• LogP: 1.83390

Purity/Quality:

97% ^*data from raw suppliers

[4-(5-Oxazolyl)phenyl]methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [4-(5-Oxazolyl)phenyl]methanol

There total 2 articles about [4-(5-Oxazolyl)phenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4-oxazol-5-ylbenzoic acid methyl ester (179057-14-8) → [4-(1,3-oxazol-5-yl)phenyl]methanol (179057-18-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 5 ℃; for 0.5h;

DOI:10.1021/jm9800853

Reference yield:

methyl 4-formylbenzoate (1571-08-0) → [4-(1,3-oxazol-5-yl)phenyl]methanol (179057-18-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / K₂CO₃ / methanol / 3.5 h / Heating

2: 87 percent / LiAlH₄ / tetrahydrofuran / 0.5 h / 5 °C

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; methanol;

DOI:10.1021/jm9800853

Reference yield:

[4-(1,3-oxazol-5-yl)phenyl]methanol (179057-18-2) → 4-(oxazol-5-yl)benzaldehyde (179057-31-9)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; Yield given. Multistep reaction; 1.) CH₂Cl₂, -60 deg C, 1 h, 2.) CH₂Cl₂, from -60 deg C to RT, 1 h;

DOI:10.1021/jm9800853

upstream raw materials:

4-oxazol-5-ylbenzoic acid methyl ester

methyl 4-formylbenzoate

Downstream raw materials:

4-(oxazol-5-yl)benzaldehyde

Cycloheptyl-(4-oxazol-5-yl-benzyl)-amine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 179057-18-2 [4-(5-Oxazolyl)phenyl]methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send