4,5-Dichloro-2-(pyridin-2-YL)pyridazin-3(2H)-one

Base Information

• Chemical Name: 4,5-Dichloro-2-(pyridin-2-YL)pyridazin-3(2H)-one
• CAS No.: 78389-19-2
• Molecular Formula: C₉H₅Cl₂N₃O
• Molecular Weight: 242.064
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID70581412
• Wikidata: Q82472544
• Mol file: 78389-19-2.mol

Synonyms:78389-19-2;4,5-DICHLORO-2-(PYRIDIN-2-YL)PYRIDAZIN-3(2H)-ONE;AKOS 90779;4,5-dichloro-2-pyridin-2-ylpyridazin-3-one;4,5-dichloro-2-(pyridin-2-yl)-2,3-dihydropyridazin-3-one;AKOS90779;4,5-dichloro-2-pyridin-2-yl-2H-pyridazin-3-one;SCHEMBL1639975;DTXSID70581412;BBFKVSHYSHBPMY-UHFFFAOYSA-N;AKOS-90779;AMY24954;BCP24817;AKOS000135510;AP-501/43286826;4,5-dichloro-2-(2-pyridinyl)-3(2H)-pyridazinone;4,5-Dichloro-2-pyridine-2-ylpyridazin-3(2H)-one;4, 5-Dichloro-2-pyridin-2-yl-2H-pyridazin-3-one, AldrichCPR

Chemical Property of 4,5-Dichloro-2-(pyridin-2-YL)pyridazin-3(2H)-one

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 331.143ºC at 760 mmHg
• Flash Point: 154.07ºC
• PSA: 47.78000
• Density: 1.546g/cm3
• LogP: 1.93430
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 240.9809672
• Heavy Atom Count: 15
• Complexity: 340

Purity/Quality:

98%min ^*data from raw suppliers

4,5-DICHLORO-2-(PYRIDIN-2-YL)PYRIDAZIN-3(2H)-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)N2C(=O)C(=C(C=N2)Cl)Cl

Technology Process of 4,5-Dichloro-2-(pyridin-2-YL)pyridazin-3(2H)-one

There total 3 articles about 4,5-Dichloro-2-(pyridin-2-YL)pyridazin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

pyrid-2-ylhydrazine (4930-98-7) + mucochloric acid (57697-64-0) → 4,5-dichloro-2-pyridine-2-ylpyridazin-3(2H)-one (78389-19-2)

Guidance literature:

With hydrogenchloride; In ethanol; water; for 2h; Reflux;

Reference yield: 75.0%

→ 4,5-dichloro-2-pyridine-2-ylpyridazin-3(2H)-one (78389-19-2)

Guidance literature:

Reference yield:

mucochloric acid (87-56-9) + 2-hydrazinopyridine monohydrochloride (51169-05-2) → 4,5-dichloro-2-pyridine-2-ylpyridazin-3(2H)-one (78389-19-2)

Guidance literature:

With sodium carbonate; acetic acid; Yield given. Multistep reaction; 1.) H₂O, 1 h + overnight, room temperature, 2.) reflux;

upstream raw materials:

mucochloric acid

2-hydrazinopyridine monohydrochloride

pyrid-2-ylhydrazine

mucochloric acid