N-(3-methoxybenzyl)ethanamine

Base Information

• Chemical Name: N-(3-methoxybenzyl)ethanamine
• CAS No.: 140715-61-3
• Molecular Formula: C10H15NO
• Molecular Weight: 165.23
• Hs Code.: 2922299090
• DSSTox Substance ID: DTXSID70405907
• Wikidata: Q82210659
• Mol file: 140715-61-3.mol

Synonyms:N-(3-methoxybenzyl)ethanamine;140715-61-3;N-Ethyl-3-methoxybenzylamine;N-[(3-methoxyphenyl)methyl]ethanamine;Benzenemethanamine, N-ethyl-3-methoxy-;MFCD07405846;SCHEMBL8279674;DTXSID70405907;CHEMBRDG-BB 5545112;STK513129;AKOS000160048;SB76134;DS-18634;SY045888;CS-0038214;A885806

Chemical Property of N-(3-methoxybenzyl)ethanamine

Chemical Property:

• Vapor Pressure: 0.0373mmHg at 25°C
• Boiling Point: 240.8°C at 760 mmHg
• Flash Point: 95.3°C
• PSA: 21.26000
• Density: 0.963g/cm³
• LogP: 2.19560
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 165.115364102
• Heavy Atom Count: 12
• Complexity: 116

Purity/Quality:

97% ^*data from raw suppliers

N-(3-Methoxybenzyl)ethanamine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNCC1=CC(=CC=C1)OC

Technology Process of N-(3-methoxybenzyl)ethanamine

There total 5 articles about N-(3-methoxybenzyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

N-Ethyl-3-methoxybenzamide (70772-76-8) → N-(3-methoxybenzyl)ethanamine (140715-61-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.5h; Heating;

DOI:10.1248/cpb.39.3225

Reference yield:

N-acetyl-(3-methoxyphenyl)methanamine (174688-81-4) → N-(3-methoxybenzyl)ethanamine (140715-61-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 70 ℃;

DOI:10.1016/j.bmcl.2008.03.026

Reference yield:

3-methoxy-benzaldehyde (591-31-1) → N-(3-methoxybenzyl)ethanamine (140715-61-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium formate; formic acid

2: aqueous hydrochloric acid

With hydrogenchloride; formic acid; sodium formate;

DOI:10.1002/ardp.19422800602

upstream raw materials:

N-ethyl-N-(3-methoxy-benzyl)-formamide

N-Ethyl-3-methoxybenzamide

3-methoxy-benzaldehyde

N-acetyl-(3-methoxyphenyl)methanamine

Downstream raw materials:

C₁₈H₁₇BrN₂O₂S

C₂₁H₂₈BrN₃O₃

C₂₃H₃₀BrN₃O₃

C₂₂H₃₁BrN₄O₂