2,4-dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine

Base Information

Chemical Name:2,4-dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine
CAS No.:237435-80-2
Molecular Formula:C12H7Cl2N3
Molecular Weight:264.114
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40441832
Wikidata:Q82258799
Mol file:237435-80-2.mol

Synonyms:2,4-dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine;237435-80-2;A4954;SCHEMBL5776765;SCHEMBL5776767;DTXSID40441832;AKOS015850414;BB 0256799;FT-0682585

Suppliers and Price of 2,4-dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2,4-Dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine 95+%
1g
$ 545.00

Chemenu
2,4-Dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine 95%
1g
$ 514.00

American Custom Chemicals Corporation
2,4-DICHLORO-6-PHENYL-5H-PYRROLO[3,2-D]PYRIMIDINE 95.00%
5G
$ 1491.68

American Custom Chemicals Corporation
2,4-DICHLORO-6-PHENYL-5H-PYRROLO[3,2-D]PYRIMIDINE 95.00%
250MG
$ 726.44

Alichem
2,4-Dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine
25g
$ 4775.76

Alichem
2,4-Dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine
10g
$ 3039.12

Alichem
2,4-Dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine
5g
$ 2150.70

Total 16 raw suppliers

Chemical Property of 2,4-dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine

Chemical Property:

Boiling Point:433.8±27.0 °C(Predicted)
PKA:10.46±0.40(Predicted)
PSA：41.57000
Density:1.487±0.06 g/cm3(Predicted)
LogP:3.93170
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:263.0017026
Heavy Atom Count:17
Complexity:271

Purity/Quality:

97% ^*data from raw suppliers

2,4-Dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC3=C(N2)C(=NC(=N3)Cl)Cl

Technology Process of 2,4-dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine

There total 4 articles about 2,4-dichloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 34771-39-6
6-phenylpyrrolo[3,2-d]pyrimidine-2,4-diol

: 237435-80-2
2,4-dichloro-6-phenylpyrrolo[3,2-d]pyrimidine

Guidance literature:: With trichlorophosphate; at 120 ℃; for 60h;
DOI:10.1021/jm000269t

Reference yield:

: 614-16-4
Benzoylacetonitrile

: 237435-80-2
2,4-dichloro-6-phenylpyrrolo[3,2-d]pyrimidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 57 percent / Et₃N / CH₂Cl₂ / 23 h / 0 - 22 °C

2.1: NaOEt / ethanol / 2 h / 20 °C

3.1: aq. AcOH / 15 h / 20 °C

3.2: 77 percent / 6percent aq. NaOH / 2 h / Heating

4.1: 40 percent / POCl₃ / 60 h / 120 °C

With sodium ethanolate; acetic acid; triethylamine; trichlorophosphate; In ethanol; dichloromethane;
DOI:10.1021/jm000269t

Reference yield:

: 237435-26-6
2-cyano-1-phenylvinyl-4-methylbenzenesulfonate

: 237435-80-2
2,4-dichloro-6-phenylpyrrolo[3,2-d]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaOEt / ethanol / 2 h / 20 °C

2.1: aq. AcOH / 15 h / 20 °C

2.2: 77 percent / 6percent aq. NaOH / 2 h / Heating

3.1: 40 percent / POCl₃ / 60 h / 120 °C

With sodium ethanolate; acetic acid; trichlorophosphate; In ethanol;
DOI:10.1021/jm000269t