{1-[(Benzyloxy)methyl]-4-iodo-1H-imidazol-5-yl}acetaldehyde

Base Information

Chemical Name:{1-[(Benzyloxy)methyl]-4-iodo-1H-imidazol-5-yl}acetaldehyde
CAS No.:949492-70-0
Molecular Formula:C13H13IN2O2
Molecular Weight:356.163
Hs Code.:
DSSTox Substance ID:DTXSID00693870
Wikidata:Q82622844
Mol file:949492-70-0.mol

Synonyms:949492-70-0;SCHEMBL2562303;DTXSID00693870;AKOS015904439;FT-0745155;{1-[(Benzyloxy)methyl]-4-iodo-1H-imidazol-5-yl}acetaldehyde

Suppliers and Price of {1-[(Benzyloxy)methyl]-4-iodo-1H-imidazol-5-yl}acetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of {1-[(Benzyloxy)methyl]-4-iodo-1H-imidazol-5-yl}acetaldehyde

Chemical Property:

PSA：44.12000
LogP:2.40340
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:356.00218
Heavy Atom Count:18
Complexity:259

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COCN2C=NC(=C2CC=O)I

Technology Process of {1-[(Benzyloxy)methyl]-4-iodo-1H-imidazol-5-yl}acetaldehyde

There total 1 articles about {1-[(Benzyloxy)methyl]-4-iodo-1H-imidazol-5-yl}acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: E/Z-1-(benzyloxy)methyl-4-iodo-5-(2-methoxyethenyl)imidazole

: 949492-70-0
1-(benzyloxy)methyl-5-(formylmethyl)-4-iodoimidazole

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 70 ℃; for 0.333333h;
DOI:10.1021/jm070447j

Reference yield:

: 949492-70-0
1-(benzyloxy)methyl-5-(formylmethyl)-4-iodoimidazole

: C₁₃H₁₃IN₂O₃

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In acetonitrile; at 20 ℃; for 1.5h;
DOI:10.1021/jm070447j

Reference yield:

: 949492-70-0
1-(benzyloxy)methyl-5-(formylmethyl)-4-iodoimidazole

: 949492-76-6
1-(benzyloxy)methyl-5-(ethoxycarbonyl)methyl-4-iodoimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaClO₂; NaH₂PO₄*H₂O; 2-methyl-2-butene / acetonitrile / 1.5 h / 20 °C

2: 0.29 g / HCl / 1 h / Heating

With hydrogenchloride; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In acetonitrile; 2: Fischer esterification;
DOI:10.1021/jm070447j