1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone

Base Information

Chemical Name:1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone
CAS No.:821794-90-5
Molecular Formula:C₁₈H₁₉ClN₄O₂
Molecular Weight:358.827
Hs Code.:2933998090
ChEMBL ID:CHEMBL515416
DSSTox Substance ID:DTXSID10586567
Nikkaji Number:J2.191.288C
Wikidata:Q82478713
Mol file:821794-90-5.mol

Synonyms:821794-90-5;CMK;1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone;CHEMBL515416;1-[4-AMINO-7-(3-HYDROXYPROPYL)-5-(4-METHYLPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-6-YL]-2-CHLORO-ETHANONE;1-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloroethanone;1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloro-ethanone-d6;1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloro-ethanone (>90%);SCHEMBL12200862;DTXSID10586567;WHB79490;BDBM50248767;AKOS030526911;CS-0404;NCGC00485901-01;HY-52101;MS-25648;F83981;1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethan-1-one;1-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone;1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloroethan-1-one;Ethanone, 1-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloro-

Suppliers and Price of 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloro-ethanone(>90%)
1mg
$ 360.00

DC Chemicals
CMK >98%
100 mg
$ 600.00

Crysdot
CMK 98+%
5mg
$ 133.00

Crysdot
CMK 98+%
10mg
$ 210.00

Crysdot
CMK 98+%
25mg
$ 364.00

ChemScene
CMK 99.64%
25mg
$ 432.00

ChemScene
CMK 99.64%
10mg
$ 300.00

ChemScene
CMK 99.64%
5mg
$ 180.00

ChemScene
CMK 99.64%
2mg
$ 120.00

Apolloscientific
CMK
1mg
$ 102.00

Total 9 raw suppliers

Chemical Property of 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone

Chemical Property:

Boiling Point:647.5±55.0 °C(Predicted)
PKA:14.43±0.10(Predicted)
PSA：94.03000
Density:1.39±0.1 g/cm3(Predicted)
LogP:3.37400
Storage Temp.:-20°C Freezer
Solubility.:Chloroform, methanol
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:358.1196536
Heavy Atom Count:25
Complexity:458

Purity/Quality:

97% ^*data from raw suppliers

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloro-ethanone(>90%) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=C(N(C3=NC=NC(=C23)N)CCCO)C(=O)CCl
Uses 1-[4-AMino-7-(3-hydroxypropyl)-5-(4-Methylphenyl)-7H-pyrrolo[2,3-d]pyriMidin-6-yl]-2-chloro-ethanone can be used in the preparation of serine/threonine kinase inhibitors.

Technology Process of 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone

There total 1 articles about 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 821794-91-6
C₂₄H₃₃ClN₄O₂Si

: 821794-90-5
C₁₈H₁₉ClN₄O₂

Guidance literature:: C₂₄H₃₃ClN₄O₂Si; With hydrogenchloride; In tetrahydrofuran; water; at 0 - 20 ℃; for 2.5h;

With sodium hydrogencarbonate; sodium chloride; In tetrahydrofuran; water; ethyl acetate;