2-(1-BENZYL-PYRROLIDIN-3-YL)-ETHYLAMINE

Base Information

• Chemical Name: 2-(1-BENZYL-PYRROLIDIN-3-YL)-ETHYLAMINE
• CAS No.: 130927-84-3
• Molecular Formula: C13H20N2
• Molecular Weight: 204.31
• Hs Code.: 2933990090
• Mol file: 130927-84-3.mol

Synonyms:[2-(1-benzylpyrrolidin-3-yl)ethyl]amine hydrochloride;2-(1-benzylpyrrolidin-3-yl)ethanamine(SALTDATA: 2HCl);1-BENZYL-PYRROLIDIN-3-YL) ETHYL-AMINE;

Chemical Property of 2-(1-BENZYL-PYRROLIDIN-3-YL)-ETHYLAMINE

Chemical Property:

• Vapor Pressure: 0.00107mmHg at 25°C
• Boiling Point: 301.1°C at 760 mmHg
• PKA: 10.42±0.10(Predicted)
• Flash Point: 125.5°C
• PSA: 29.26000
• Density: 1.024g/cm³
• LogP: 2.49550
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-(1-Benzyl-3-pyrrolidinyl)ethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(1-BENZYL-PYRROLIDIN-3-YL)-ETHYLAMINE

There total 6 articles about 2-(1-BENZYL-PYRROLIDIN-3-YL)-ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

((S)-1-Benzyl-pyrrolidin-3-yl)-acetonitrile (303111-44-6) → 2-((R)-1-Benzyl-pyrrolidin-3-yl)-ethylamine (303111-45-7,130927-84-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃; for 0.5h;

DOI:10.1016/S0960-894X(00)00405-4

Reference yield:

(R)-1-benzylpyrrolidine-3-carbonitrile (157528-56-8) → 2-((R)-1-Benzyl-pyrrolidin-3-yl)-ethylamine (303111-45-7,130927-84-3)

Guidance literature:

Multi-step reaction with 6 steps

1: conc. HCl / 0.5 h / Heating

2: SOCl₂ / 16 h / -50 - 20 °C

3: LiAlH₄ / diethyl ether / -30 °C

4: NEt₃ / tetrahydrofuran / 0.5 h / -23 °C

5: dimethylsulfoxide / 5 h / 60 °C

6: 98 percent / LiAlH₄ / diethyl ether / 0.5 h / 0 - 20 °C

With hydrogenchloride; lithium aluminium tetrahydride; thionyl chloride; triethylamine; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide; 1: Hydrolysis / 2: Esterification / 3: Reduction / 4: mesylation / 5: Substitution / 6: Reduction;

DOI:10.1016/S0960-894X(00)00405-4

Reference yield:

methyl (R)-(-)-1-(phenylmethyl)-3-pyrrolidinecarboxylate (216311-59-0) → 2-((R)-1-Benzyl-pyrrolidin-3-yl)-ethylamine (303111-45-7,130927-84-3)

Guidance literature:

Multi-step reaction with 4 steps

1: LiAlH₄ / diethyl ether / -30 °C

2: NEt₃ / tetrahydrofuran / 0.5 h / -23 °C

3: dimethylsulfoxide / 5 h / 60 °C

4: 98 percent / LiAlH₄ / diethyl ether / 0.5 h / 0 - 20 °C

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide; 1: Reduction / 2: mesylation / 3: Substitution / 4: Reduction;

DOI:10.1016/S0960-894X(00)00405-4

upstream raw materials:

((S)-1-Benzyl-pyrrolidin-3-yl)-acetonitrile

(R)-1-benzylpyrrolidine-3-carbonitrile

methyl (R)-(-)-1-(phenylmethyl)-3-pyrrolidinecarboxylate

(R)-(+)-1-(phenylmethyl)-3-hydroxymethylpyrrolidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

✦Write with AI

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 130927-84-3 2-(1-BENZYL-PYRROLIDIN-3-YL)-ETHYLAMINE

Send

Send

Metric Ton KG G Pound L ML

Send

Send