3,5-difluoro-4-iodopyridine

Base Information

• Chemical Name: 3,5-difluoro-4-iodopyridine
• CAS No.: 1116099-07-0
• Molecular Formula: C₅H₂F₂IN
• Molecular Weight: 240.979
• Hs Code.: 2933399090
• Mol file: 1116099-07-0.mol

Synonyms:3,5-Difluoro-4-iodo-pyridine;

Chemical Property of 3,5-difluoro-4-iodopyridine

Chemical Property:

• Boiling Point: 184.2±35.0 °C(Predicted)
• PKA: -1.00±0.28(Predicted)
• PSA: 12.89000
• Density: 2.129±0.06 g/cm3(Predicted)
• LogP: 1.96440
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,5-Difluoro-4-iodopyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-difluoro-4-iodopyridine

There total 1 articles about 3,5-difluoro-4-iodopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-difluoropyridine (71902-33-5) → 3,5-difluoro-4-iodopyridine (1116099-07-0)

Guidance literature:

3,5-difluoropyridine; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In diethyl ether; hexane; at -78 ℃; Inert atmosphere;

With iodine; In diethyl ether; hexane; at -78 - 20 ℃;

Reference yield:

3,5-difluoro-4-iodopyridine (1116099-07-0) + 4-Ethynylaniline (14235-81-5) → 4-((3,5-difluoropyridin-4-yl)ethynyl)aniline

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine; In water; at 80 ℃;

upstream raw materials:

3,5-difluoropyridine

Refernces

• 1、 -. "SUBSTITUTED ACYLGUANIDINE DERIVATIVE". Page/Page column 10. . Retrieved 2012/01/03.