3-(6-Bromo-pyridin-3-yl)-acrylic acid

Base Information

• Chemical Name: 3-(6-Bromo-pyridin-3-yl)-acrylic acid
• CAS No.: 1035123-89-7
• Molecular Formula: C8H6BrNO2
• Molecular Weight: 228.04
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID80696900
• Mol file: 1035123-89-7.mol

Synonyms:DTXSID80696900;MZIMKUQFGDVIID-UHFFFAOYSA-N;3-(6-bromo-pyridin-3-yl)-acrylic acid;FT-0773966

Chemical Property of 3-(6-Bromo-pyridin-3-yl)-acrylic acid

Chemical Property:

• PSA: 50.19000
• LogP: 1.94190
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 226.95819
• Heavy Atom Count: 12
• Complexity: 194

Purity/Quality:

98%min ^*data from raw suppliers

3-(6-Bromopyridin-3-yl)acrylicacid 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NC=C1C=CC(=O)O)Br

Technology Process of 3-(6-Bromo-pyridin-3-yl)-acrylic acid

There total 1 articles about 3-(6-Bromo-pyridin-3-yl)-acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3-(6-bromo-pyridin-3-yl)-acrylic acid methyl ester (918305-33-6) → 3-(6-bromo-pyridin-3-yl)-acrylic acid (1035123-89-7)

Guidance literature:

3-(6-bromo-pyridin-3-yl)-acrylic acid methyl ester; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 3h;

With hydrogenchloride; water; pH=5 - ~ 7;

upstream raw materials:

3-(6-bromo-pyridin-3-yl)-acrylic acid methyl ester

Refernces