Methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide)

Base Information

• Chemical Name: Methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide)
• CAS No.: 118495-99-1
• Molecular Formula: C29H43AlBr2O2
• Molecular Weight: 610.449
• Mol file: 118495-99-1.mol

Synonyms:

Chemical Property of Methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide)

There total 2 articles about Methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-2,6-di-tert-butylphenol (1139-52-2) + trimethylaluminum (75-24-1) → methylaluminium bis(4-bromo-2,6-di-tert.-butylphenoxide) (118495-99-1)

Guidance literature:

In dichloromethane; byproducts: CH4; to soln. of the phenol (2 equiv in CH2Cl2) added Me3Al (1 equiv in hexane, room temp.), stirred at room temp. for 1h; not isolated;

Reference yield:

trimethylaluminium dimer + 4-bromo-2,6-di-tert-butylphenol (1139-52-2) → methylaluminium bis(4-bromo-2,6-di-tert.-butylphenoxide) (118495-99-1)

Guidance literature:

In hexane; dichloromethane; byproducts: CH4; addn. of 1 equiv. of Me3Al in hexane to 4-bromo-2,6-di-t-butylphenoxide (2 equiv.) in CH2Cl2 at room temp. under Ar (evolution of CH4 gas); stirring of colorless soln. at room temp. for 1 h; not isolated from soln.;

DOI:10.1246/bcsj.65.541

Reference yield: 48.0%

methylaluminium bis(4-bromo-2,6-di-tert.-butylphenoxide) (118495-99-1) + tert-Butyl-((2S,3S)-3-isopropyl-3-methyl-oxiranylmethoxy)-dimethyl-silane (141812-25-1,141812-40-0) → 2-(tert-Butyl-dimethyl-silanyloxymethyl)-2,3-dimethyl-butyraldehyde (141812-26-2) + 2,6-Di-tert-butyl-4-[2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-phenol (141812-28-4) + 4-Bromo-2-tert-butyl-6-[2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-phenol (141812-27-3)

Guidance literature:

In dichloromethane; at -78 - -20 ℃;

DOI:10.1016/0040-4020(92)85006-Z

upstream raw materials:

4-bromo-2,6-di-tert-butylphenol

trimethylaluminum

Downstream raw materials:

2-(tert-Butyl-dimethyl-silanyloxymethyl)-2,3-dimethyl-butyraldehyde

2,6-Di-tert-butyl-4-[2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-phenol

4-Bromo-2-tert-butyl-6-[2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-phenol

(R)-4-(benzyloxy)-2-((tert-butyldimethylsilyloxy)methyl)-2-methylbutanal