Olmesartan Medoxomil Methyl Ether

Base Information

• Chemical Name: Olmesartan Medoxomil Methyl Ether
• CAS No.: 896419-17-3
• Molecular Formula: C30H32N6O6
• Molecular Weight: 572.61
• Mol file: 896419-17-3.mol

Synonyms:Olmesartan Medoxomil Methyl Ether;4-(1-Methoxy-1-Methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1H-iMidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl Ester;OlMesartan MedoxoMil iMpurity II

Chemical Property of Olmesartan Medoxomil Methyl Ether

Chemical Property:

• Boiling Point: 769.6±70.0 °C(Predicted)
• PKA: 4.15±0.10(Predicted)
• PSA: 151.16000
• Density: 1.33±0.1 g/cm3(Predicted)
• LogP: 4.82410
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

OlmesartanMedoxomilMethylEther ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Impurity of Olmesartan Medoxomil

Technology Process of Olmesartan Medoxomil Methyl Ether

There total 1 articles about Olmesartan Medoxomil Methyl Ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

4-(1-methoxy-1-methylethyl)-2-propyl-1-{4-(2-trityltetrazol-5-yl)phenyl}phenylmethylimidazole-5-carboxylic acid-5-methyl-2-oxo-[1,3]-dioxolene-4-yl-methyl ester (1040405-56-8) → 4-(1-methoxy-1-methylethyl)-2-propyl-1-{4-(2-tetrazol-5-yl)phenyl}phenylmethylimidazole-5-carboxylic acid-5-methyl-2-oxo-[1,3]-dioxolene-4-yl-methyl ester (896419-17-3)

Guidance literature:

With formic acid; In methanol; dichloromethane; at 40 ℃; for 6h;

DOI:10.1002/jhet.5570450342

upstream raw materials:

4-(1-methoxy-1-methylethyl)-2-propyl-1-{4-(2-trityltetrazol-5-yl)phenyl}phenylmethylimidazole-5-carboxylic acid-5-methyl-2-oxo-[1,3]-dioxolene-4-yl-methyl ester

Refernces