4-(3,4-Dichlorophenyl)phenol

Base Information

Chemical Name:4-(3,4-Dichlorophenyl)phenol
CAS No.:53890-77-0
Molecular Formula:C12H8Cl2O
Molecular Weight:239.0973
Hs Code.:
DSSTox Substance ID:DTXSID60968672
Nikkaji Number:J2.899.552K
Wikidata:Q82951539
Mol file:53890-77-0.mol

Synonyms:4-(3,4-dichlorophenyl)phenol;53890-77-0;3',4'-Dichloro-[1,1'-biphenyl]-4-ol;3,4-Dichloro-4'-hydroxybiphenyl;3',4'-Dichloro-(1,1'-biphenyl)-4-ol;3',4'-dichloro-biphenyl-4-ol;3',4'-dichlorobiphenyl-4-ol;SCHEMBL6335821;DTXSID60968672;UTTIPSVNOWSCRD-UHFFFAOYSA-N;MFCD11932375;AKOS017565191;1,1'-Biphenyl-4-ol, 3',4'-dichloro;3',4'-Dichloro[1,1'-biphenyl]-4-ol;BS-32536;CS-0209236

Suppliers and Price of 4-(3,4-Dichlorophenyl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
4-(3,4-DICHLOROPHENYL)PHENOL
5g
$ 1943.00

Rieke Metals
4-(3,4-DICHLOROPHENYL)PHENOL
1g
$ 809.00

Crysdot
3',4'-Dichloro-[1,1'-biphenyl]-4-ol 97%
5g
$ 452.00

Acrotein
3',4'-Dichloro-biphenyl-4-ol 97%
5g
$ 540.83

Total 5 raw suppliers

Chemical Property of 4-(3,4-Dichlorophenyl)phenol

Chemical Property:

Boiling Point:367.2°Cat760mmHg
Flash Point:140.8°C
PSA：20.23000
Density:1.35g/cm³
LogP:4.36600
XLogP3:4.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:237.9952203
Heavy Atom Count:15
Complexity:202

Purity/Quality:

99%, ^*data from raw suppliers

4-(3,4-DICHLOROPHENYL)PHENOL ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC(=C(C=C2)Cl)Cl)O

Technology Process of 4-(3,4-Dichlorophenyl)phenol

There total 1 articles about 4-(3,4-Dichlorophenyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 106-41-2
4-bromo-phenol

: 151169-75-4
3,4-dichlophenylboronic acid

: 53890-77-0
4′-hydroxy-3,4-dichlorobiphenyl

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 95 ℃;
DOI:10.1016/S0968-0896(03)00303-1

Reference yield:

: 53890-77-0
4′-hydroxy-3,4-dichlorobiphenyl

: methyl (2-((3',4'-dichloro-(1,1'-biphenyl)-4-yl)oxy)pyridin-3-yl)(methoxy)carbamate

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / mineral oil; toluene / 0.5 h / 100 °C

1.2: Reflux

2.1: sodium acetate; tin(II) chloride dihdyrate / tetrahydrofuran; water; methanol / 0 °C

3.1: sodium hydrogencarbonate / tetrahydrofuran / -10 °C

4.1: potassium carbonate / acetone / 12 h / 0 - 20 °C / Sealed tube

With tin(II) chloride dihdyrate; sodium acetate; sodium hydride; sodium hydrogencarbonate; potassium carbonate; In tetrahydrofuran; methanol; water; acetone; toluene; mineral oil;
DOI:10.1016/j.bmc.2018.01.004

Reference yield:

: 53890-77-0
4′-hydroxy-3,4-dichlorobiphenyl

: methyl (2-((3',4'-dichloro-[1,1'-biphenyl]-4-yl)oxy)pyridin-3-yl)(hydroxy)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / mineral oil; toluene / 0.5 h / 100 °C

1.2: Reflux

2.1: sodium acetate; tin(II) chloride dihdyrate / tetrahydrofuran; water; methanol / 0 °C

3.1: sodium hydrogencarbonate / tetrahydrofuran / -10 °C

With tin(II) chloride dihdyrate; sodium acetate; sodium hydride; sodium hydrogencarbonate; In tetrahydrofuran; methanol; water; toluene; mineral oil;
DOI:10.1016/j.bmc.2018.01.004