6-Bromo-4-nitro-1H-indazole

Base Information

Chemical Name:6-Bromo-4-nitro-1H-indazole
CAS No.:885518-46-7
Molecular Formula:C7H4BrN3O2
Molecular Weight:242.032
Hs Code.:2933990090
Mol file:885518-46-7.mol

Synonyms:6-bromo-4-nitro-indazole; 1H-Indazole,6-bromo-4-nitro

Suppliers and Price of 6-Bromo-4-nitro-1H-indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Bromo-4-nitro-1H-indazole
250mg
$ 100.00

TRC
6-Bromo-4-nitro-1H-indazole
10g
$ 1075.00

SynQuest Laboratories
6-Bromo-4-nitro-1H-indazole 97%
5 g
$ 750.00

SynQuest Laboratories
6-Bromo-4-nitro-1H-indazole 97%
1 g
$ 225.00

Sigma-Aldrich
6-Bromo-4-nitro-1H-indazole Aldrich
1g
$ 168.00

Matrix Scientific
6-Bromo-4-nitro-1H-indazole 95%
500mg
$ 39.00

Matrix Scientific
6-Bromo-4-nitro-1H-indazole 95%
5g
$ 180.00

Matrix Scientific
6-Bromo-4-nitro-1H-indazole 95%
1g
$ 60.00

Labseeker
6-bromo-4-nitro-1H-indazole 97
50g
$ 2700.00

J&W Pharmlab
6-Bromo-4-nitro-1H-indazole 97%
1g
$ 58.00

Total 48 raw suppliers

Chemical Property of 6-Bromo-4-nitro-1H-indazole

Chemical Property:

Boiling Point:420.8±25.0 °C(Predicted)
PKA:9.86±0.40(Predicted)
PSA：74.50000
Density:1.965
LogP:2.75680
Storage Temp.:Inert atmosphere,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

6-Bromo-4-nitro-1H-indazole ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Uses 6-Bromo-4-nitro-1H-indazole is a reagent in the preparation of 1,2,4-triazine-6-carboxamide derivatives having acetamide group as Syk kinase inhibitors for the treatment of cancer, allergy, or autoimmune diseases.

Technology Process of 6-Bromo-4-nitro-1H-indazole

There total 4 articles about 6-Bromo-4-nitro-1H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 864550-40-3
5-bromo-2-methyl-3-nitroaniline

: 885518-46-7
6-bromo-4-nitro-1H-indazole

Guidance literature:: With acetic acid; sodium nitrite; at 20 ℃; for 12h;

Reference yield: 62.0%

: 885518-46-7
6-bromo-4-nitro-1H-indazole

Guidance literature:: With acetic acid; sodium nitrite; In water; at 0 - 20 ℃; for 6h;

Reference yield:

: 606-20-2
2,6-dinitrotoluene

: 885518-46-7
6-bromo-4-nitro-1H-indazole

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione / 15 h / 20 °C

2: hydrogenchloride; iron / methanol; 1,4-dioxane; water / 12 h / 80 °C

3: acetic acid; sodium nitrite / 12 h / 20 °C

With hydrogenchloride; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; sulfuric acid; iron; acetic acid; sodium nitrite; In 1,4-dioxane; methanol; water;