Trans-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid

Base Information

Chemical Name:Trans-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid
CAS No.:80896-74-8
Molecular Formula:C₁₈H₁₈ClNO₂
Molecular Weight:315.799
Hs Code.:
DSSTox Substance ID:DTXSID401001621
Mol file:80896-74-8.mol

Synonyms:80896-74-8;Trans-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid;trans-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid HCl;SCHEMBL8210627;DTXSID401001621;(3R,4S)-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid;AKOS015856008;AKOS015898010;F21182;Trans-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylicacid

Suppliers and Price of Trans-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TRANS-1-BENZYL-4-(4-CHLOROPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID 95.00%
10G
$ 1334.03

American Custom Chemicals Corporation
TRANS-1-BENZYL-4-(4-CHLOROPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID 95.00%
5G
$ 909.56

Total 11 raw suppliers

Chemical Property of Trans-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:472.479°C at 760 mmHg
Flash Point:239.547°C
Density:1.281g/cm³
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:315.1026065
Heavy Atom Count:22
Complexity:375

Purity/Quality:

97% ^*data from raw suppliers

TRANS-1-BENZYL-4-(4-CHLOROPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C(CN1CC2=CC=CC=C2)C(=O)O)C3=CC=C(C=C3)Cl
Isomeric SMILES:C1[C@@H]([C@H](CN1CC2=CC=CC=C2)C(=O)O)C3=CC=C(C=C3)Cl

Technology Process of Trans-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid

There total 14 articles about Trans-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: (3R,4S)-1-Benzyl-4-(4-chloro-phenyl)-pyrrolidine-3-carboxylic acid methyl ester

: 80896-74-8,1417789-28-6
trans-1-benzyl-4-(p-chlorophenyl)pyrrolidine-3-carboxylic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1016/j.bmcl.2007.10.032

Reference yield: 99.0%

: 1229236-32-1
1-Benzyl-4-(4-chloro-phenyl)-2,5-dihydro-1H-pyrrole-3-carboxylic acid

: 1229236-26-3,80896-74-8,1417789-28-6
(3S,4S)-1-Benzyl-4-(4-chloro-phenyl)-pyrrolidine-3-carboxylic acid

Guidance literature:: With hydrogen; [Ru(OAc)2((S)-2-Furyl-MeOBIPHEP)]; In methanol; at 30 ℃; for 20h; under 30003 Torr; Product distribution / selectivity;