Ombrabulin hydrochloride

Base Information

Chemical Name:Ombrabulin hydrochloride
CAS No.:253426-24-3
Deprecated CAS:253609-44-8
Molecular Formula:C21H27ClN2O6
Molecular Weight:438.908
Hs Code.:
European Community (EC) Number:682-340-5
UNII:KXZ9NDO6H0
DSSTox Substance ID:DTXSID50426074
Wikidata:Q27282491
ChEMBL ID:CHEMBL585539
Mol file:253426-24-3.mol

Synonyms:AC 7700;AC-7700;AVE8062;N-(2-methxoy-5-(2-(3,4,5-trimethoxyphenyl)vinyl)pheyl)-serinamide hydrochloride;ombrabulin

Suppliers and Price of Ombrabulin hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Ombrabulinhydrochloride 99.84%
1mg
$ 180.00

ChemScene
Ombrabulinhydrochloride 99.84%
5mg
$ 420.00

ChemScene
Ombrabulinhydrochloride 99.84%
10mg
$ 600.00

ChemScene
Ombrabulinhydrochloride 99.84%
50mg
$ 1800.00

ChemScene
Ombrabulinhydrochloride 99.84%
100mg
$ 2520.00

DC Chemicals
Ombrabulinhydrochloride >98%
250 mg
$ 700.00

DC Chemicals
Ombrabulinhydrochloride >98%
100 mg
$ 400.00

Total 7 raw suppliers

Chemical Property of Ombrabulin hydrochloride

Chemical Property:

PSA：115.76000
LogP:4.30130
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:9
Exact Mass:438.1557643
Heavy Atom Count:30
Complexity:517

Purity/Quality:

97% ^*data from raw suppliers

Ombrabulinhydrochloride 99.84% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)NC(=O)C(CO)N.Cl
Isomeric SMILES:COC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)NC(=O)[C@H](CO)N.Cl
Recent EU Clinical Trials:A multinational, randomized, double-blind placebo controlled study of AVE8062 (25 mg/m2) administered every 3 weeks in patients with advanced-stage soft tissue sarcoma, treated with cisplatin (75 mg/m2) after failure of anthracycline and ifosfamide chemotherapies.

Technology Process of Ombrabulin hydrochloride

There total 10 articles about Ombrabulin hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%