tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate

Base Information

Chemical Name:tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate
CAS No.:1179360-20-3
Molecular Formula:C11H22N2O3
Molecular Weight:230
Hs Code.:2933990090
Mol file:1179360-20-3.mol

Synonyms:tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate;tert-butyl 3-(hydroxyMethyl)-1,4-diazepane-1-carboxylate-HCl;1-Boc-3-(HydroxyMethyl)-1,4-diazepane

Suppliers and Price of tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-Boc-3-(Hydroxymethyl)-1,4-diazepane 95+%
1g
$ 1580.00

Chemenu
1-Boc-3-(Hydroxymethyl)-1,4-diazepane 95%
1g
$ 1477.00

American Custom Chemicals Corporation
1-BOC-3-(HYDROXYMETHYL)-1,4-DIAZEPANE 95.00%
5MG
$ 505.02

Alichem
1-Boc-3-(Hydroxymethyl)-1,4-diazepane
1g
$ 1674.80

Total 19 raw suppliers

Chemical Property of tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate

Chemical Property:

PSA：61.80000
LogP:0.84440
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

1-Boc-3-(Hydroxymethyl)-1,4-diazepane 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate

There total 3 articles about tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 389062-86-6
(1,4-diazepan-2-yl)methanol

: 1179360-20-3
tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water-d2; at 0 ℃; for 3h;

Reference yield:

: 847556-35-8
ethyl 1,4-dibenzyl-1,4-diazepane-2-carboxylate

: 1179360-20-3
tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 0 - 20 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 2068.65 Torr / Inert atmosphere

3: sodium hydroxide / 1,4-dioxane; water-d2 / 3 h / 0 °C

With lithium aluminium tetrahydride; palladium 10% on activated carbon; hydrogen; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; water-d2;

Reference yield:

: (1,4-dibenzyl-1,4-diazepan-2-yl)methanol

: 1179360-20-3
tert-butyl 3-(hydroxymethyl)-1,4-diazepane-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / methanol / 2068.65 Torr / Inert atmosphere

2: sodium hydroxide / 1,4-dioxane; water-d2 / 3 h / 0 °C

With palladium 10% on activated carbon; hydrogen; sodium hydroxide; In 1,4-dioxane; methanol; water-d2;